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Your search keyword '"Gimenez-Gallego, Guillermo"' showing total 6 results
Start Over Author "Gimenez-Gallego, Guillermo" Topic chemistry
6 results on '"Gimenez-Gallego, Guillermo"'

1. Hints of nonhierarchical folding of acidic fibroblast growth factor

Author

Sanz, Jesus M., Jimenez, M. Angeles, and Gimenez-Gallego, Guillermo

Subjects
Biochemistry -- Research, Growth factors -- Physiological aspects, Fibroblasts -- Physiological aspects, Acids -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the all-beta protein acidic fibroblast growth factor and the peptides involved in the receptor binding. The helical propensity of the growth factor and the peptides has been investigated via the use of the circular dichroism and proton nuclear magnetic resonance.

Published
2002

2. Partial IGF affinity of circulating N- and C-terminal fragments of human insulin-like growth factor binding protein-4 (IGFBP-4) and the disulfide bonding pattern of the C-terminal IGFBP-4 domain

Author

Standker, Ludger, Braulke, Thomas, Mark, Silke, Mostafavi, Hossein, Meyer, Markus, Honing, Stefan, Gimenez-Gallego, Guillermo, and Forssmann, Wolfe-Georg

Subjects
Biochemistry -- Research, Sulfides -- Research, Insulin -- Research, Growth factors -- Analysis, Carrier proteins -- Research, Chemical bonds -- Analysis, Biological sciences, Chemistry
Abstract

Research has been conducted on the insulin-like growth factor-binding proteins. Results include molecular characterization of circulating human IGFBP-4 fragments that have been formed in vivo.

Published
2000

3. (super)1 H NMR structural characterization of a nonmitogenic, vasodilatory, ischemia-protector and neuromodulatory acidic fibroblast growth factor

Author

Lozano, Rosa M., Pineda-Lucena, Antonio, Gonzalez, Carlos, Jimenez, M. Angeles, Cuevas, Pedro, Redondo-Horcajo, Mariano, Sanz, Jesus M., Rico, Manuel, and Gimenez-Gallego, Guillermo

Subjects
Biochemistry -- Research, Mitogens -- Research, Vasodilators -- Analysis, Ischemia -- Causes of, Fibroblast growth factors -- Research, Amino acids -- Research, Biological sciences, Chemistry
Abstract

Research has been conducted on the acidic fibroblast growth factor (aFGF). The vasodilatory activity of the aFGF has been investigated.

Published
2000

4. Intravitreal Dobesilate Injection for Macular Oedema Secondary to Branch Retinal Vein Occlusion

Author

Outeiriño Luis Antonio, Angulo Javier, Azanza Carlos, Cuevas Sanchez Pedro, and Gimenez-Gallego Guillermo

Subjects
medicine.medical_specialty, Central retinal vein, Visual acuity, genetic structures, business.industry, Macular oedema, Retinal, General Medicine, medicine.disease, eye diseases, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Ophthalmology, Occlusion, medicine, Branch retinal vein occlusion, sense organs, medicine.symptom, business, Vein, Retinal haemorrhage
Abstract

We describe a patient with macular oedema secondary to occlusion of two branches of the central retinal vein, who has been treated with a single intravitreal injection of dobesilate. Three months after treatment, visual acuity reached 1, with an anatomical resolution of the macular oedema and the retinal haemorrhage. To our knowledge this is the first case reporting a resolution of macular oedema associated to branch retinal vein occlusions after a single intravitreal injection of dobesilate.

Published
2016

5. Conformational flexibility of a synthetic glycosylaminoglycan bound to a fibroblast growth factor. FGF-1 recognizes both the (super 1)C(sub 4) and (super 2)S(sub 0) conformations of a bioactive heparin-like hexasaccharide

Author

Canales, Angeles, Angulo, Jesus, Ojeda, Rafael, Bruix, Marta, Fayos, Rosa, Lozano, Rosa, Gimenez-Gallego, Guillermo, Martin-Lomas, Manuel, Nieto, Pedro M., and Jimenez-Barbero, Jesus

Subjects
Fibroblast growth factors -- Research, Polypeptides -- Atomic properties, Polypeptides -- Structure, Conformational analysis, Chemistry
Abstract

A study is conducted which describes the biological, structural, and conformational details of the binding of glycosylaminoglycans (GAGs) to polypeptides of the fibroblast growth factor (FGF) family, the chemokines, and to antithrombin-III (AT-III). The results obtained indicate that within the complex with FGF-1, the iduronate rings of the bound oligosaccharide display a conformational equilibrium between the (super 1)C(sub 4) and (super 2)S(sub 0) forms.

Published
2005

6. Solution structure of RicC3, a 2S albumin storage protein from Ricinus communis

Author

Pantoja-Uceda, David, Bruix, Marta, Gimenez-Gallego, Guillermo, Rico, Manuel, and Santoro, Jorge

Subjects
Albumin -- Structure, Castor beans -- Research, Castor oil plant -- Research, Structure-activity relationships (Biochemistry) -- Analysis, Proteins -- Analysis, Proteins -- Structure, Biological sciences, Chemistry
Abstract

Research describes the three-dimensional solution structure of recombinant RicC3 albumin protein from the castor beans. The core structure display a RMSD radius of 0.64 Angstroms. The nuclear magnetic resonance structure shows five amphipatic helices in a right-handed super helix, unique to this lipid transfer protein. r

Published
2003

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