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Hyperterpenoid A (1) and B (2), two pairs of enantiomers, with an unprecedented 6/6/4/6/6 polycyclic skeleton, along with one known compoud hypermonone A (3) were isolated from Hypericum beanii. The racemate (±)-1 and (±)-2 were successfully separated into the two optically pure enantiomers (ee ≥ 99%) using a preparative HPLC system. Their absolute configurations were elucidated by extensive spectroscopic analyses and single-crystal X-ray diffraction method. The related plausible biogenetic pathways were presented. Compound 1-3 showed significant neuroprotective activity and potential anti-inflammatory activity. The result that (+)-2 and (-)-2 presented different anti-inflammatory properties, may lead us to new discovery of structure activity relationship between racemates, enantiomers, and diastereomers, as well as further research regarding the binding of drugs to target proteins.

Three new diterpenoids (1–3) and three new esterifying lignans (4–6) were isolated from the leaves of Tripterygium wilfordii. The structures of these compounds were elucidated on the basis of spectroscopic techniques (UV, IR, NMR, HRESIMS, and ECD method). At 10 μmol/L, compounds 4–6 showed moderate inhibitory effects on nitric oxide production in LPS-induced macrophages with inhibitory rate >80%.

High density ZnO nanostructures were fabricated on Au coated Si and quartz substrates through once and the same oxidative evaporation of pure zinc powder. The coated side of the substrate was intentionally positioned in two directions of face and back to the zinc sources. Structure, morphology and optical properties of the samples were investigated by scanning electron microscopy, X-ray diffraction, Raman spectra and room temperature photoluminescence measurements. The results showed that the samples on the different substrates with different directions have three different morphologies, including film-, rod- and comb-like nanostructures. Photoluminescence spectra of the samples showed the various bands centered in UV (380-390 nm), blue (470-490 nm), green (500-550 nm) and orange (610-620 nm) region. It demonstrates that the substrate material and the direction of substrate significantly affect the growth of ZnO nanostructures.