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Start Over Author "Peter Merry" Topic chemistry
4 results on '"Peter Merry"'

1. Iron free radicals and arthritis

Author

Peter Merry, Tulin Sahinoglu, R. E. Allen, D R Blake, Alya Dabbagh, Christopher Morris, and Cliff R. Stevens

Subjects
medicine.medical_specialty, Nutrition and Dietetics, Free Radicals, Chemistry, Arthritis, Iron, Radical, Synovial Membrane, Medicine (miscellaneous), Iron Deficiencies, Iron deficiency, medicine.disease, Endocrinology, Ischemia, Reperfusion Injury, Internal medicine, Pressure, medicine, Humans, Joints
Published
1990
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2. Oxidative damage to lipids within the inflamed human joint provides evidence of radical-mediated hypoxic-reperfusion injury

Author

J Lunec, D R Blake, Peter Merry, and Martin Grootveld

Subjects
musculoskeletal diseases, Adult, Male, Antioxidant, Knee Joint, medicine.medical_treatment, Physical Exertion, Medicine (miscellaneous), Pharmacology, Lipid peroxidation, Arthritis, Rheumatoid, chemistry.chemical_compound, Reperfusion therapy, Synovitis, Synovial Fluid, Medicine, Synovial fluid, Humans, Aged, Nutrition and Dietetics, business.industry, Hypoxia (medical), Middle Aged, medicine.disease, chemistry, Spectrophotometry, Reperfusion Injury, Immunology, Female, Lipid Peroxidation, medicine.symptom, business, Reperfusion injury
Abstract

Previous work has established the existence of a pathophysiological environment within the inflamed human joint, capable of sustaining a hypoxic-reperfusion event. Using four different assay systems (two standard and two novel) applied to synovial fluid for the assessment of lipid peroxidation, a series of studies demonstrate that exercise of the inflamed human knee promotes radical-mediated lipid peroxidation within the joint. The implication for novel antioxidant therapeutic approaches to inflammatory joint disease is discussed. more...

Published
1991

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3. Oxidants, Joint Inflammation and Anti-Inflammatory Strategies

Author

V R Winrow, Ewa J Dr Dowling, David R. Blake, and Peter Merry

Subjects
chemistry.chemical_classification, Reactive oxygen species, chemistry, medicine.drug_class, medicine, chemistry.chemical_element, Inflammation, Molecular oxygen, medicine.symptom, Adjuvant arthritis, Oxygen, Anti-inflammatory, Cell biology
Abstract

Biological reduction of molecular oxygen in cells is accompanied by the production of dangerously reactive free radical and non-radical oxygen species. Because of the ubiquity of molecular oxygen and its ability to accept electrons, their production is readily associated with cellular damage1. more...

Published
1990
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