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Your search keyword '"Sho, Hatano"' showing total 4 results
Start Over Author "Sho, Hatano" Topic chemistry
4 results on '"Sho, Hatano"'

1. Library-directed Solution- and Solid-phase Synthesis of 2,4-Disubstituted Pyridines: One-pot Approach through 6 π-Azaelectrocyclization

Author

Hiroshi Tsuchikawa, Sho Hatano, Toyoharu Kobayashi, Shigeo Katsumura, Taku Sakaguchi, Koichi Fukase, and Katsunori Tanaka

Subjects
chemistry.chemical_classification, Spectrometry, Mass, Electrospray Ionization, Pyridines, Organic Chemistry, Spectrometry, X-Ray Emission, Stereoisomerism, Sequence (biology), General Chemistry, Silanes, Biochemistry, Catalysis, Sulfonamide, Solutions, Chromatographic separation, chemistry.chemical_compound, Solid-phase synthesis, chemistry, Cyclization, Pyridine, Vinyl iodide, Combinatorial Chemistry Techniques, Organic chemistry, Palladium catalyst, Linker, Palladium
Abstract

An efficient one-pot synthetic procedure for the synthesis of 2,4-disubstituted pyridines has been successfully established. The method proceeds through a 6pi-azaelectrocyclization-aromatization sequence. Using this method, a wide variety of pyridine structures substituted at the 2-position have been rapidly constructed from vinyl stannanes, vinyl iodide, sulfonamide, and a palladium catalyst. The method was further applied to the solid-phase synthesis wherein the use of a "traceless" sulfonamide linker enabled the rapid preparation of a small library of pyridines with high purity, without any chromatographic separation.

Published
2009

2. A novel strategy for the synthesis of 2-arylpyridines using one-pot 6π-azaelectrocyclization

Author

Shigeo Katsumura, Sho Hatano, Toyoharu Kobayashi, and Hiroshi Tsuchikawa

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Pyridine synthesis, chemistry, Organic Chemistry, Drug Discovery, Pyridine, Aromatization, Base (exponentiation), Biochemistry, Combinatorial chemistry, Sulfonamide
Abstract

A novel and useful method for the synthesis of 2-arylpyridines with a high efficiency and generality was achieved by utilizing the one-pot 6π-azaelectrocyclization followed by a base treatment. This is the first example of applying a sulfonamide to the azaelectrocyclization for efficient substituted pyridine synthesis.

Published
2008

3. ChemInform Abstract: A Novel Strategy for the Synthesis of 2-Arylpyridines Using One-Pot 6π-Azaelectrocyclization

Author

Toyoharu Kobayashi, Shigeo Katsumura, Hiroshi Tsuchikawa, and Sho Hatano

Subjects
chemistry.chemical_classification, Pyridine synthesis, Chemistry, Nanotechnology, General Medicine, Base (exponentiation), Combinatorial chemistry, Sulfonamide
Abstract

A novel and useful method for the synthesis of 2-arylpyridines with a high efficiency and generality was achieved by utilizing the one-pot 6π-azaelectrocyclization followed by a base treatment. This is the first example of applying a sulfonamide to the azaelectrocyclization for efficient substituted pyridine synthesis.

Published
2008

4. Cross Metathesis Route in Sphingomyelin Synthesis

Author

Shigeo Katsumura, Sho Hatano, Toshikazu Hakogi, Hiroko Hasegawa, and Tetsuya Yamamoto

Subjects
chemistry.chemical_compound, Sphingosine, Chemistry, Yield (chemistry), Sphingomyelin synthesis, Salt metathesis reaction, Stereoselectivity, General Chemistry, General Medicine, Metathesis, Combinatorial chemistry, Catalysis
Abstract

Cross metathesis reaction of short chain Boc sphingosine using Grubbs’ 2nd generation catalyst proceeded in stereoselective manner to afford Boc sphingosine in good yield. An efficient synthesis of...

Published
2005

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