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Background Coronary artery disease is the most important cause of death in industrialized countries. Diabetes mellitus is one of the most important modifiable risk factors of coronary artery disease. It increases the risk of coronary artery disease by 2 to 4-fold. Interestingly, this increased risk is not confined to patients with DM, but non-diabetic patients with impaired glucose tolerance (IGT) also may have an increased incidence of cardiovascular complications. Moreover, increased admission glucose levels may be related to a higher mortality rates in patients with acute myocardial infarction (AMI), regardless of diabetic status. Objective To assess the prognostic impact of admission HbA1c in patients without known diabetes mellitus who were admitted with acute ST elevation myocardial infarction, on outcome of 1ry PCI and short-term outcome of adverse cardiac events. Material and Methods This is an observational, this study was conducted at Coronary care unit & coronary catheterization lab unit of cardiology department in Ain Shams University & specialized hospitals. The study period was 6 months (From 1-9-2018 till 1-3-2019). Results 100 patients without prior diagnosis of DM were included in our study population Three categories of patients were created according to HbA1c level: Group 1 (< 5.7%): 46 patients (46%); Group 2 (5.5 to 6.4%): 38patients (38%); Group 3 (>6.5%): 16 patients (16%). Baseline characteristics of the study population are shown in Table 1. The mean age of our sample was 55.06 ± 11.73 years and 96% were males. There was highly statistically significant difference found between DM groups regarding SYNTAX score with P-value (0.002) & another highly significant difference in EF between the 3 groups. Conclusion The present study showed that admission higher HbA1c level in non-diabetic patients presented by acute STEMI is associated with more severe CAD, lower rate of complete revascularization TIMI 3, and higher incidence of adverse cardiac events and mortality. Introducing measurement of HbA1c in the CCU seems to be a simple method to obtain important information on mortality risk.

Endosulfan is an insecticide from the organochlorine group which was last banned in Indonesia in 2013. Endosulfan is very effective in controlling for organisms pest management and is widely used, including for controlling pest of shallot plants. The objective of the research to determine the distribution of endosulfan residues that has been carried out in three villages representing intensive shallot planting areas in Brebes Regency. The three villages were Wanasari, Siasem, and Pebatan in Wanasari sub-District. Soil sampling was carried out in June-July 2019. The prediction area of the residual endosulfan distribution in the research was 1,853 ha. The analysis of endosulfan residues was carried out in the integrated laboratory of the Indonesian Agricultural Environment Research Institute, using the QuECheRS method. From 14 soil sampling points, eleven of them were detected containing endosulfan residues exceeding Maximum Residues Limit (MRLs) of 0.0085 mg kg−1. The distribution of endosulfan residues was mapping using the spline interpolation method and divided into five categories very low, low, medium, high, very high. Interpolation showed 68.47% of the land experienced very high endosulfan residual pollution (>0.0117 mg kg−1). These results showed that pollute agricultural land need to get priority on land remediation for sustainable agriculture.

In this study, we report a novel approach for preparing precipitated calcium carbonate for the first time by Bacillus licheniformis using different types of media containing urea as a source of urease enzyme and for the first time using particles of pure calcium. The bacteria used in this study produced urease which catalyzes the hydrolysis of urea (CO(NH 2 ) 2 ) into ammonium (NH 4 ) and carbonate (CO 3 2− ) leading to the precipitation of calcium carbonate. Calcium carbonate precipitation was experimentally studied by spontaneous precipitation at various pH (8–12), temperatures (30, 35, 40, 45, 50 °C), and at different concentrations of urease enzyme (1, 5, 10 mg mL −1 ). The XRD results showed a mixture of calcite and vaterite. The morphology of calcium carbonate particles prepared was studied under SEM after using it as a bioconsolidation of degraded fresco wall paintings.

Bacterial-induced mineralization has been explored for protection and consolidation of degraded limestone, concrete and plaster by precipitation of calcium carbonate. It is the first time that Bacillus sphaericus was used for consolidating the nonsterilized decayed wall paintings samples by immersing them in sterile nutritional media. The B. sphaericus used in this study produced urease, which catalyzes the hydrolysis of urea (CO(NH2)2) into ammonium (NH4) and carbonate (CO3−2) leading to the precipitation of calcium carbonate. The effect of B. sphaericus on wall paintings was determined by recording the evolution of culture media chemistry and examining the treated wall paintings under a scanning electron microscope to show the structural and morphological evolution of calcium carbonate that was investigated in wall paintings models.

This paper describes a simple way for the coating of magnetite nanoparticles (MNPs) with amorphous silica. First, MNPs were synthesized by controlled co-precipitation technique under N2 gas and then their surface was modified with trisodium citrate in order to achieve particles with improved dispersibility. Afterward, magnetite-silica core/shell nanocomposites were prepared by a sol–gel approach, using magnetic fluid including electrostatically stabilized MNPs as seeds. The prepared samples were characterized by means of X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared (FT-IR) spectroscopy, zeta potential analysis and vibrating sample magnetometer (VSM) in order to study their structural and magnetic properties. FT-IR and XRD results imply that resultant nanocomposites are consisted of two compounds; Fe3O4 and SiO2 and TEM images confirm formation of their core/shell structure. TEM images also show increase in silica shell thickness from ∼5 to ∼24 nm with increase in amount of tetraethyl orthosilicate (TEOS) used during the coating process from 0.1 to 0.3 mL. Magnetic studies indicate that Fe3O4 nanoparticles remain superparamagnetic after coating with silica although their Ms values are significantly less than pristine MNPs. These core/shell nanocomposites offer a high potential for different biomedical applications due to having superparamagnetic property of magnetite and unique properties of silica.

A new class of 7-azaindole analogs of MK-7246 as potent and selective CRTH2 antagonists is reported. The SAR leading to the identification of the optimal azaindole regioisomer as well as the pharmacokinetics and off-target activities of the most potent antagonists are disclosed.

A new technique for investigation of the electrical effects of micropipes in single-crystal 6H-SiC is presented. The setup allows the application of a parallel or normal electric field to MSM (metal-semiconductor-metal) test structures and the visualization of light emission sites in the test gap, including light activity underneath the metal contact. A special transparent metal [indium-tin-oxide(ITO)] was chosen for the metallic contacts. A map of micropipe locations was initially obtained at zero applied field using a laser scattering method. The initial map is compared with that of light emissions at different applied fields.Several tests on undoped and vanadium-doped (compensated) SiC, using NiCr/Au or ITO contacts, indicated the rapid activation of micropipes at relatively low fields in vertical MSM devices. A good match between the laser imaging map of micropipes at zero field and the map of field-induced light emission sites indicates that micropipes are the main current paths in vertical devices, carrying a large current density, and leading to light emissions and partial or total bulk breakdown of the test device.

Sandstone samples from the Temple of Karnak, Luxor, Egypt, were studied by X-ray diffraction (XRD), thin-section analysis and scanning electron microscopy (SEM). Physical, mechanical and thermal properties were determined before and after treatment with six different consolidants. The data were confirmed by SEM examination. Methyl trimethoxy silane (MTMOS) gave the best results in the consolidation of the Karnak sandstone.