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Elderly is defined as an age group that is susceptible to various diseases. The aging process in the elderly is associated with an increase in oxidative stress activity which can lead to various health problems which are a major cause of high mortality and morbidity. This study aimed to analyze the effect of supplementation of catfish (Clarias gariepinus) oil enriched with omega-3 soft capsule on oxidative stress and cognitive function of elderly people. The design of this study was a single blind randomized control trial. A total of 29 elderly subjects were chosen following these inclusion criteria: aged >60 y; had dyslipidemia; and signed the informed consent. Subject were divided into three groups i.e. SO (soybean oil), CFO (commercial fish oil), and CO with omega-3 (catfish oil enriched with omega-3). The intervention was 1,000 mg oil/d administered for 90 d. The results showed that different supplementation groups had significant effects on oxidative stress and cognitive function (p

This study aimed to determine the effect of high-protein milk intervention on weight gain and renal function in malnourished children. This research is a randomized controlled trial (RCT). A total of 52 wasting children (BAZ -3

This study aimed to examine the potential of white tea and kelor in improving lipid profile and histopathological features of the pancreas in streptozotocin-induced Sprague-Dawley rats. The research design was an experimental study with post-test control group design. Catechin content were analysed using High-Performance Liquid Chromatography. Twenty Sprague-Dawley rats (out of 24 rats, 12-week old, 200-300 g) were induced with intraperitoneal injection of streptozotocin at a dose of 40 mg/kg BW. Four groups of rats received one of the green tea (GT), white tea (WT), kelor (K), or the mixture of white tea and kelor (WTK) with a dose of epigallocatechin-3-gallate (EGCG) at 100 mg/kg BW administered orally for 21 days. Measurements of the lipid profile and preparation of histopathological features of the pancreas were performed after the intervention was completed. The results showed that white tea had the highest concentrations of catechin (39.17%), gallic acid (1.09%), EGCG (4.46%), and epicatechin (9.61%) compared to the other tea groups. The TG levels of the WTK group (95±19.35 mg/dl) were significantly different (p 0.05). The mean diameter of the islets of Langerhans in the DM group (9.16± 2.56 μm) was significantly different (p

The objective of this study is to investigate the effect of moringa leaves powder which is packed in a capsule to the uric acid level of pre-elderly and elderly. The subjects of this study were 24 pre-elderlies and elderlies which were 47 years old and older. These subjects were divided into two groups, one was given 2g of moringa leaves powder and the other was given 3g of moringa leaves powder. The experiment was conducted for 14 days. The subjects’ blood sample was taken to measure their uric acid level. The result of this study indicated that moringa leaves capsule's intervention decreased the uric acid level as demonstrated by the measurement in Day-7 and Day-14. Therefore, this research concluded that moringa capsule intervention for 14 days had an ability to decrease uric acid level.

The objective of this study is to identify the effect of moringa leaves products consumption in the form of moringa capsule and moringa tea on the elderly’s uric acid level. The study design was quasi-experiment. The subjects of this study were 16 elderlies which were all 47 years old or older. These subjects were divided into two groups. First, the group that was given 1 package of moringa tea (equal to 1.5g moringa tea). Second, the group that was given 2 moringa capsules (equal to ± 0.5g moringa leaves powder). Both products were set to be consumed twice a day (morning and afternoon). Both products contain antioxidant activity (IC50-DPPH) for approximately 139.93 ppm. The consumption of moringa capsule for seven days consecutively has a potential effect on the medicinal treatment of hyperuricemia by decreasing uric acid level.

Unsaturated fatty acids contained oils which sensitive to oxidation caused by heat, light andoxygen. The oxidized oil known harmful to the body. One of the effort to prevent the oxidationprocess is by adding antioxidants stability of oil catfish and shelf life of the oil. The experimentalstudy was applied by adding vitamin E to the oil as much as 0.67 mg / g PUFA compared with thecontrol oil. Oil was stored with the Schaal Oven Test method, which are stored at a temperatureof 600C. The study showed that, based on the parameters of oxidation (free fatty acids, peroxidevalue, anisidin numbers, and the number of total oxidation), catfish oil were added vitamin Emore stabilized than the catfish oil without added vitamin E. The catfish fish oil in the form of softgell capsules added vitamin E could maintain stability in appropriate with IFOS up to 23 months.Keywords: Catfish oil, vitamin E, stability, Schaal Oven Test

Degenerative process is an accumulation of free radicals that can lead to a variety of changes in the cell. This aim of the study to see the effects of different dietary lipid intervention on lipid profile and lipid peroxidation in female aged cynomolgus monkey. Twelve female Cynomolgus monkey (Macaca fascicularis) were randomly divided into 4 dietary groups of three animals. Animals were held in individual cages and placed in the position where they can interact individually. They were given a normal fat diet with 2% cholesterol and 3% of fat from soybean oil and 9% of lipid as beef tallow (BFT), catfish oil (CFO), fermented catfish oil (FCFO) and soybean oil (SBO). Evaluation of their body weights, serum lipid profile and cholesterol content consumption were done monthly except an index of lipid peroxidation were performed before and after 12 weeks intervention. Animal group that consumed the feed more than 82% has body weight gain, such as CFO and BFT. On the other side, animal group that consumed less than 70% has body weight loss, such as FCFO. There was no effect (p > 0.05) of the experimental diets on decreasing triglyceride levels and increasing HDL cholesterol level. Cynomolgous given BFT, CFO, and FCFO diet for 3 months showed signifi cantly increased (p < 0.05) in total cholesterol and LDL cholesterol level, but the monkeys fed with SBO showed lower levels. Statistically, All of diet interventions do not significantly affect on lipid peroxidation in LDL (p < 0.05). In general it can be concluded that catfish oil significantly cause elevated levels of total cholesterol and LDL cholesterol in blood serum, but not in the HDL plasma. DOI : http://dx.doi.org/10.17576/JSKM-2014-1202-03

COMPLEMENTARY FOOD DEVELOPMENT BASED ON PUPAE-MULBERRY (PURY) Proper complementary feeding are well recognized as necessary to ensure optimal growth and development during the early years, however are often inadequate in energy density, protein and micronutrient concentration. The aim of the study is to develop pury-formula complementary foods for infant aged 6-9 moths and to analyze nutrition quality and food safety. A silkworm pupae was a major constituents used as materials which was processed to be a fine powder, called “PURY”. Methods: mix all ingredients consist of 16.6% red rice flour, 16.6% tempe powder, 16.6% formula milk powder, 25% fine sugar cane and 25% pury. Results and finding: Per 100 g Pury-formula contain 426 kcal energy, 20.0% protein, 11.2% fat included linoleat and linolenat; vitamin A,E, B groups and mineral such as Fe, Ca, Zinc, Iodine and Se. Conclusion: Pury-formula complementary food is better than commercial product and as well as Health Department guidance. It has a well balanced amount of energy, protein, carbohydrate, fat included long chain polyunsaturated fatty acids (LC-PUFAs) that are essential for the brain and optimal growth of infants. Recommendation: Pury-formula can be an alternate nutritious complementary food for infants undernourished. Keywords : pury, complementary food, growth, infant, undernourished

The objective of this study was to produce arrowroot starch flakes with dumbo catfish (Clarias gariepinus) flour, as a rich energy, protein, and mineral food for elderly. Design of this study was complete randomized design with four formulas and each combination was replicated two times. A selected formula was determined based on semi trained panelists preference. Acceptance of selected flakes formula was examined by elderly using hedonic test. Flakes by addition of 33.00% of dumbo catfish flour was the selected formula. The chemical properties for selected flakes were as follows 4.00% of water, 4.84% ash, 16.90% protein, 5.21% fat, 69.06% carbohydrate, 14.48% calcium, and 8.61% phosphor. The selected flakes contain 391 kcals energy per 100 g. The selected flakes had contributed more than 20.00% of energy, protein, calcium, and phosphor for elderly people so it can be claimed as a food product rich in energy, protein and minerals.Keywords: arrowroot starch, dumbo catfish flour, flakes, mineral, proteinABSTRAKTujuan penelitian ini adalah untuk menghasilkan flakes pati garut dan tepung ikan lele dumbo (Clarias gariepinus) sebagai pangan kaya energi, protein, dan mineral untuk lansia. Desain penelitian menggunakan Rancangan Acak Lengkap dengan empat formula dan setiap kombinasi diulang dua kali. Formula terpilih ditentukan berdasarkan preferensi panelis agak terlatih. Penerimaan flakes terpilih oleh lansia dilakukan dengan menggunakan uji hedonik. Flakes dengan penambahan tepung ikan lele dumbo sebanyak 33.00% merupakan formula terpilih. Sifat kimia flakes terpilih yaitu 4.00% kadar air, 4.84% abu, 16.90% protein, 5.21% lemak, 69.06% karbohidrat, 14.48% kalsium, dan 8.61% fosfor. Flakes terpilih mengandung 391 kkal energi per 100 g. Flakes terpilih memiliki kontribusi lebih dari 20.00% untuk energi, protein, mineral kalsium, dan fosfor untuk lansia sehingga dapat diklaim sebagai produk makanan yang kaya energi, protein, dan mineral.Kata kunci: flakes, mineral, pati garut, protein, tepung ikan lele dumbo

The chlorophyll is well known as natural antioxidant which is commonly high level in some geen leafy and has potential biological effect for a good health and has been proved has antioxidant and antimutagenic activity. In fact, a high content of chlorophyll is available in nature but in contrast its found commercially in Indonesia as imported product with a high price. The objectives of this study were to determine of chlorophyll level of various leaves (Premna oblongifolia Merr., Saurpus androgynus Merr. Centella asiatica, and Morus alba L), to produce copper-chlorophyll derivative powder, and to observe its physico-chemical properties. The research showed that cincau leaf had higher level of chlorophyll than other leaves, meanwhile cincau leaf used as material of copper-chlorophyll derivative. Cincau leaves chlorophyll extract solution with Cu2+ 100 mg/l level produce the cincau copper-chlorophyll derivative powder with highest pH, solubility, and geenness compare to other copper levels. The cincau copper-derivate chlorophyll powder contained chlorophyll 3986 mg/kg, b-carotene 33.8 mg/kg, and contained alkaloid, saponin, tanin, steroid, and glycoside. Keywords: chlorophyll, Premna oblongifolia Merr., Saurpus androgynus Merr., Centella asiatica, Morus alba L., copper-chlorophyll derivative