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Introduction: Dichloromethane (DCM) and trichloroethylene (TCE) are both common halohydrocarbons which are widely used in industry. The most common exposure route of DCM or TCE is inhalation, but intramuscular injection of DCM and TCE is very rarely. Case presentation: A 47-year-old male presented ecchymosis, pain, and swelling of the left limb following accident injection of ABS glue (main ingredients were DCM and TCE). The swelling of his left limb was lasted until day 6 and WBC, NEUT, CK, CK-MB, LDH, AST and ALT were elevated until day 9. He was received intravenous fluids, analgesic, antibiotics, and other supportive measures and finally discharged from the hospital on day 16. Discussion: Both DCM and TCE could cause local irritation and systemic toxicity involving central nervous system, liver, kidney and other organs. In this case, because the small dose of toxicant and injection being the route of exposure, the patient mainly suffered from local toxicity resulting in painful soft tissue swelling with slight hemocytology and biochemistry disorder. Although there are no specific antidotes for DCM and TCE poisoning, supportive measures may also provide satisfactory therapeutic results. Conclusions: DCM and TCE poisoning following intramuscular injection could present mainly with local and system poisoning symptoms and successfully treated with supportive measures.

A reliable and efficient hairy root induction system for the important medicinal plant Callerya speciosa was established by optimizing several parameters that affected the efficiency of Agrobacterium rhizogenes-mediated transformations. Four strains, A4, LBA9402, R1601 and C58C1, and four types of explants, hypocotyls, cotyledons, leaves and excised stems, were examined and the highest rate of transformation (68.3 %) was obtained in cotyledons using strain LBA9402. Therefore, the optimum co-cultivation time and acetosyringone (AS) concentration were evaluated for LBA9402-infected cotyledons and determined to be 2 days and 100 µM AS, respectively, resulting in 64.4 and 66.7 % hairy root transformation efficiency rates, respectively. Transgenic hairy root lines were confirmed by PCR amplification and Southern blot. The growth trend of hairy roots was “slow-quick-slow” and peaked after 30 days of culturing, with increases of 11-fold and 11.4-fold of fresh and dry weights respectively, compared with initial inoculation. Hairy roots showed the ability to synthesize polysaccharides. The effects of different media Murashige and Skoog (MS), ½ MS, WPM and B5, and carbon sources, sucrose, glucose, fructose and maltose on the growth and polysaccharide production of hairy roots were also studied. The ½ MS medium was found to be superior, resulting in the highest accumulation of biomass (10.9 g L−1 fresh weight and 1.1 g L−1 dry weight), the maximum growth index (9.96) and polysaccharide content (22.56 mg g−1 dry weight). Sucrose at 30 g L−1 was optimal for both biomass accumulation and polysaccharide production.

The study on multi-component or competitive gas–solid adsorption process is a challenge to current theories as well as experimental methods. In the paper, a methodology composed of near-infrared spectroscopy, process analytical technique and chemometrics has been tried to investigate the adsorption process of orthoxylene/aniline onto active alumina surface. The adsorption process took place in a differential adsorption bed, which was non-invasively monitored by a near-infrared spectrometer via optical fiber probe, and spectra were collected at every minute during the whole adsorption process. After treating these spectra with chemometrics algorithms, including wavelet analysis, partial least squares and artificial neural network, the adsorption process has been investigated thoroughly as well as clearly: not only the adsorption rates of each adsorbates at various adsorption times but also a great deal of information about the mechanism of the adsorption process. For example, orthoxylene was adsorbed evenly on the active alumina surface, while aniline was adsorbed uprightly; aniline was adsorbed to fabricate the first and the second adsorption layer on the adsorbent surface simultaneously rather than to construct them in sequence or step by step; and some parts of the adsorbent surface was more active for adsorption.

This paper demonstrates the application of near-infrared process analytical technology to investigate the kinetics as well as the interaction between adsorbate molecule and adsorbent surface during a gas–solid (isoamyl alcohol vapor-silica gel) adsorption process. The adsorption process took place in a differential adsorption bed, which was temperature- and mass-homogeneous, and was in-line monitored by a near-infrared spectrometer via an optical fiber probe. After pretreating near-infrared data with band selection and partial least squares, a calibration model of back propagation-artificial neural network has been constructed to quantitatively determine the amount of adsorbate onto the adsorbent surface at any time within the entire adsorption process, the prerequisite for studying adsorption kinetics. The interaction between adsorbate and adsorbent could be acquired from the near-infrared spectra of the adsorbent adsorbing the adsorbate continuously. What is perhaps more important, since the kinetics da...

Purpose: Research Qumai total flavonoids induced diabetic mice model of streptozotocin. Methods: 12 h after fasting groups of mice, Tail vein injection of citrate buffer chain urea with cephalosporins solution (80mg/kg,0.02ml/10g), To 1 times a day. In dosing 10, 20, 30 days tail blood glucose measurement value. On the 30th day fasting 12 h after the last for 1 h, Some blood, Measuring blood glucose、Glycosylation of serum protein, Serum insulin、Insulin resistance value;After the death in mice,Take the liver glycogen original value;Take the pancreas, and kidneys,10% formalin fixed liquid, As a pathological. Results: Compared with model group、blank group, each dose of dianthus superbus flavonoids to chain urea with cephalosporins cause diabetes in mice model can significantly improve the experiment indexes. Conclusion: Dianthus superbus flavonoids to chain urea with cephalosporins caused diabetes in mice model has good therapeutic effect.

With an experimental setup of near-infrared process analytical chemistry, a competitive adsorption process of orthoxylene and aniline vapor onto silica gel has been revealed in the paper. The mixture vapor of orthoxylene and aniline has been introduced into a quartz adsorption bed, which was filled with adsorbent of silica gel and monitored continuously by a near-infrared spectrometer. Based on near-infrared spectra recorded during the adsorption process and chemometrics methodologies, the competitive adsorption process has been studied completely as well as clearly: 1) at about 62 minutes the adsorption achieved its equilibrium or stable state with aniline concentration of 0.22 g/g, and without any orthoxylene; 2) othoxylene was adsorbed first, but then rapidly replaced by aniline; 3) the adsorption of aniline resulted from the hydrogen bonds between aniline’s amino groups and silica gel’s silanol groups while that of orthoxylene was due to physical adsorption; 4) aniline was adsorbed vertically on the silica gel but orthoxylene laid evenly; 5) some surface of silica gel was more active for adsorption than others.

The effect of propanetriol on the electrochemical properties of nanofumed silica gel of Valve-regulated lead-acid (VRLA) batteries have been investigated by means of cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), transmission electron microscope (TEM) and linear sweep voltammetry (LSV). The results show that with the adding of propanetriol the redox peak current density of the lead electrode greatly increases and the reaction resistance reduces obviously. Additionally, the oxygen reactions take place less easily in the gels containing propanetriol. The content of the additive propanetriol also relates with the gel properties. It is proved that the electrochemical properties of gel contained excessive propanetriol (4wt. %) are not as good as that contain 1wt.%~3wt.%.

ZrO2 thin films were deposited by using an electron beam evaporation technique on three kinds of lithium triborate (LiB3O5 or LBO) substrates with the surfaces at specified crystalline orientations. The influences of the LBO structure on the structural and optical properties of ZrO2 thin films are studied by spectrophotometer and x-ray diffraction. The results indicate that the substrate structure has obvious effects on the structural and optical properties of the film: namely, the ZrO2 thin film deposited on the X-LBO, Y-LBO and Z-LBO orients to m(-212), m(021) and o(130) directions. It is also found that the ZrO2 thin film with m(021) has the highest refractive index and the least lattice misfit.