1. Chemokines and chemokine receptors in susceptibility to HIV-1 infection and progression to AIDS.
- Author
-
Chatterjee A, Rathore A, Vidyant S, Kakkar K, and Dhole TN
- Subjects
- Acquired Immunodeficiency Syndrome genetics, Acquired Immunodeficiency Syndrome virology, Chemokines genetics, Disease Progression, Genetic Variation immunology, Host-Pathogen Interactions, Humans, Receptors, Chemokine genetics, Receptors, HIV genetics, Receptors, HIV immunology, Acquired Immunodeficiency Syndrome immunology, Chemokines immunology, Disease Susceptibility immunology, HIV-1 immunology, Receptors, Chemokine immunology
- Abstract
A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor or co-receptor competitor and influences the susceptibility to HIV-1 infection and progression to AIDS in HIV-1 infected individuals.
- Published
- 2012
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