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Start Over Author "Bresciano, E." Topic chemotaxis, leukocyte
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1. Studies on the inhibitory effects of caffeoylquinic acids on monocyte migration and superoxide ion production.

Author

Peluso G, De Feo V, De Simone F, Bresciano E, and Vuotto ML

Subjects
Amino Acid Sequence, Cells, Cultured, Humans, Molecular Sequence Data, Monocytes cytology, Monocytes metabolism, N-Formylmethionine Leucyl-Phenylalanine pharmacology, Quinic Acid analogs & derivatives, Quinic Acid isolation & purification, Chemotaxis, Leukocyte drug effects, Monocytes drug effects, Plants, Medicinal cytology, Quinic Acid pharmacology, Superoxides metabolism
Abstract

Three caffeoylquinic acids, isolated from the Peruvian plants Tessaria integrifolia and Mikania cordifolia that are used medicinally as anti-inflammatory agents, were tested for their activities on monocyte migration and superoxide anion production. 3,5-Di-O-caffeoylquinic and 4,5-di-O-caffeoylquinic acids exhibited an appreciable anti-inflammatory activity in vitro, while the tricaffeoyl derivative was inactive.

Published
1995
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