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Background: In this study, we wanted to draw attention to the spontaneous pneumomediastinum which rarely seen and to share our experiences. Materials and Methods: Between April 2016 - April 2018, we retrospectively evaluated 12 patients who were hospitalized and treated with SPM diagnosis at Health Practice and Research Center. Results: Of the 12 patients with spontaneous pneumomediastinum, 9 (75%) were male and 3 (25%) were female. Patients had a mean age of 30.5 years (range 15-42 years), 2 patients admitted to the emergency service with swelling and dyspnea complaints, 1 patient with cough and vomiting, 1 patient with cough and chest pain, 3 patients with dyspnea and chest pain, 3 patients with sore throat and chest pain, 2 patients with swelling in the neck after the tooth extraction. 6 (50%) of the patients had a smoking history. Conclusions: Spontaneous pneumomediastinum is a disease that is seen rarely in emergencies and should be treated. Sometimes life-threatening complications may develop. Other disorders in differential diagnosis should be eliminated in spontaneous pneumomediastinum. [ABSTRACT FROM AUTHOR]