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Background: Pilomatricoma is a common but easily misdiagnosed tumor in children. Aims: To differentiate pilomatricoma from other common subcutaneous nodules in children. Patients/Methods: Misdiagnosed subcutaneous nodules in four children were recorded. Results: A red mass on a 7‐year‐old boy's head which had been misdiagnosed pyogenic granuloma was proved to be pilomatricoma. A red mass on an 8‐month‐old boy's face which had been misdiagnosed infantile hemangioma also turned to be pilomotricoma. A red mass on a 21‐month‐old girl's breast, which had been misdiagnosed pilomatricoma, was proved to be infantile myofibroma. A subcutaneous nodule under a 13‐month‐old girl's armpit, which had been misdiagnosed pilomatricoma, turned to be BCG‐associated lymphadenitis. Conclusions: When a child with a subcutaneous nodule attends, pilomatricoma, vascular tumors, fibrous tumors, and BCG‐associated lymphadenitis should be considered. [ABSTRACT FROM AUTHOR]