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Background and Objectives: Neighborhood socioeconomic disadvantage is associated with lower neurocognitive scores and differences in brain structure among school-age children. Associations between positive neighborhood characteristics, infant brain activity, and cognitive development are underexplored. We examined direct and indirect associations between neighborhood opportunity, brain activity, and cognitive development., Methods: This longitudinal cohort study included infants from 2 primary care clinics in Boston and Los Angeles. Using a sample of 65 infants, we estimated path models to examine associations between neighborhood opportunity (measured by the Child Opportunity Index), infant electroencephalography (EEG) at 6 months, and infant cognitive development (measured using the Mullen Scales of Early Learning) at 12 months. A mediation model tested whether EEG power explained associations between neighborhood opportunity and infant cognition., Results: Neighborhood opportunity positively predicted infant absolute EEG power across multiple frequency bands: low ( b = 0.12, 95% CI 0.01-0.24, p = 0.04, = 0.21); high ( b = 0.11, 95% CI 0.01-0.21, p = 0.03, = 0.23); ( b = 0.10, 95% CI 0.00-0.19, p = 0.04, = 0.20); and ( b = 0.12, 95% CI 0.02-0.22, p = 0.02, = 0.24). The results remained statistically significant after applying a Benjamini-Hochberg false discovery rate of 0.10 to adjust for multiple comparisons. No significant associations emerged between neighborhood opportunity, relative EEG power, and infant cognition. Mediation was not significant., Conclusion: Neighborhood opportunity is positively associated with some forms of infant brain activity, suggesting that positive neighborhood characteristics may play a salient role in early development., Competing Interests: The authors declare no conflict of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

The neighborhood literature consistently documents associations between neighborhood socioeconomic status (SES) and child development. Yet, this approach may miss important heterogeneity in neighborhood resources (e.g., libraries, doctors' offices) that have important implications for children. Moreover, the mechanisms that explain the relation between neighborhood characteristics and child outcomes are poorly understood. Using a sample of 955 children situated in preschool neighborhoods across nine United States cities, the present study aimed to (1) describe the relation between neighborhood SES and resources among our sample neighborhoods and (2) explore whether neighborhood SES and resources may be (a) independently and (b) jointly associated with young children's gains in language/literacy and executive function skills via differences in preschool classroom process quality. Our results suggested that neighborhoods were heterogeneous in both SES and resources, thereby indicating a diverse range of resource availability among lower SES neighborhoods. Moreover, we found that both neighborhood SES and resources were individually associated with benefits to children's development through levels of classroom process quality and that these associations were magnified in communities that were particularly high in both SES and resources. These findings point to potential policy levers at both neighborhood and classroom levels to support children's development., (© 2021 Society for Community Research and Action.)

• Study takes comprehensive view of absenteeism by considering home and classroom contexts. • Relations between absenteeism and child outcomes varied by levels of classroom quality. • Exposure to high-quality classrooms buffers negative association with children's approaches to learning. • High household stimulation buffers negative association with children's literacy skills. • Household stimulation did not buffer negative association with children's math skills. Although prior research has shown that preschoolers' absenteeism is negatively associated with their learning and developmental outcomes, few studies have examined the conditions under which absenteeism matters more versus less. This study reproduces research exploring differences in these associations across different levels of preschool classroom quality and extends this literature by considering the role of children's home learning environments. Using data from the Head Start Family and Child Experiences Survey, 2009 Cohort, results showed that associations between children's absenteeism rates and children's language, literacy, and approaches to learning skills varied by levels of classroom quality experienced. These joint associations differed by development outcome. Moreover, high levels of household stimulation were found to buffer the negative associations between absenteeism and children's literacy skills. Finally, results showed little evidence for meaningful differences in the associations between children's absenteeism, classroom quality, and developmental outcomes based on levels of household stimulation. Findings highlight the importance of considering how the classroom environments they are missing and the home environments they may be experiencing when absent from school matter for young children's development. [ABSTRACT FROM AUTHOR]