1. Omicron Infections in Vaccinated Pediatric Solid Organ Transplant Recipients.
- Author
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McAteer, John, Kalluri, Divya D, Abedon, Rivka R, Qin, Caroline X, Auerbach, Scott R, Charnaya, Olga, Danziger-Isakov, Lara A, Ebel, Noelle H, Feldman, Amy G, Hsu, Evelyn K, Mohammad, Saeed, Perito, Emily R, Thomas, Ashley M, Chiang, Teresa P Y, Garonzik-Wang, Jacqueline M, Segev, Dorry L, Werbel, William A, and Mogul, Douglas B
- Subjects
BREAKTHROUGH infections ,COVID-19 ,IMMUNIZATION ,IMMUNOGLOBULINS ,COVID-19 vaccines ,CORONAVIRUS spike protein ,PATIENTS ,FISHER exact test ,RISK assessment ,SEVERITY of illness index ,SURVEYS ,DISEASE prevalence ,IMMUNOENZYME technique ,DESCRIPTIVE statistics ,SOCIODEMOGRAPHIC factors ,DATA analysis software ,TRANSPLANTATION of organs, tissues, etc. ,DISEASE risk factors ,SYMPTOMS ,CHILDREN - Abstract
SARS-CoV-2 infection during the Omicron period was frequent amongst a cohort of vaccinated pediatric solid organ transplant recipients (pSOTRs) despite robust anti-receptor-binding domain (anti-RBD) antibody response, suggesting poor neutralizing capacity against Omicron subvariants. Breakthrough infections among pSOTRs were overall limited in severity. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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