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AIM: To observe and analyze the changes of macular retina thickness in children with occult high myopia and its influencing factors.METHODS: A prospective, non-randomized, contemporaneous controlled trial. From September 2019 to September 2020, 56 children(110 eyes)who first visited the ophthalmic clinic of the Affiliated Hospital of Chengde Medical College without any myopia correction training were enrolled in this study. According to the clinical manifestations of myopia in children, they were divided into occult high myopia group(27 cases, 52 eyes)and control group(29 cases, 58 eyes, children with common myopia). The retina thickness in each macular area was compared between the two groups, and we will analyze the correlation between macular fovea mean retinal thickness and baseline data in children with occult high myopia. RESULTS: The average retinal thickness of 9 macular regions in the occult high myopia group was thinner than that in the control group, and there were significant differences in the macular fovea, the blow and temporal side of the outer ring area of macular fovea(P-2.00D to -3.00D(P0.05). Pearson correlation analysis results showed that the average retinal thickness under macular fovea in children with secretive high myopia had no significant correlation with gender, age, eye axis, intraocular pressure and corneal curvature(P>0.05), but was negatively correlated with diopter(r=-0.201, P

High myopia is a serious eye disease that jeopardizes the visual function of children because of the irreversible changes it caused to the fundus of the eye. High myopia needs to be detected, diagnosed and treated as early as possible, if not intervened in time, it may cause further aggravation or even blindness. However, screening for myopia often encounters the situation that children with low myopia at first who are found to have high myopia fundus changes by further examinations, and these insidious high myopia changes are easily overlooked in the diagnostic process. The study aims to summarize the literatures on choroidal thickness changes and their influencing factors in myopia children, which in order to provide relevant evidence for clinical studies in children with secretive high myopia.