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On 6 February 2023, two 7.8 magnitude earthquakes consecutively hit south-central Türkiye, causing great concern from all governments, the United Nations, academia, and all sectors of society. Analyses indicate that there is also a high possibility of strong earthquakes with a magnitude of 7.8 or above occurring in the western region of China in the coming years. China is a country that is highly susceptible to catastrophic disasters such as earthquakes, floods, and other natural calamities, which can cause significant damages to both human life and property, as well as widespread impacts on the society. Currently, China's capacity for disaster prevention and control is still limited. In order to effectively reduce the impact of catastrophic disasters, ensure the safety of people's lives and property to the greatest extent possible, maintain social stability in high-risk areas, and ensure high-quality and sustainable regional development, it is urgent to improve the seismic resistance level of houses and critical infrastructure in high earthquake risk zones and increase the earthquake-resistant design level of houses in high-risk fault areas with frequent seismic activities; significantly enhance the ability to defend against extreme weather and ocean disasters in economically developed areas along the southeastern coast, as well as the level of fortification in response to extreme meteorological and hydrological disasters of coastal towns/cities and key infrastructure; vigorously enhance the emergency response capacity and disaster risk prevention level in western and ethnic minority regions; comprehensively improve the defense level of residential areas and major infrastructure in high geological hazard risk zones with flash floods, landslides, and mudslides; systematically promote national disaster prevention and mitigation education; and greatly enhance the societal disaster risk reduction ability, including catastrophic insurance. [ABSTRACT FROM AUTHOR]

HPV vaccine can prevent HPV infection effectively. The college student's vaccination status is unclear in mainland China. We assessed the knowledge, practice, and attitude towards HPV vaccine and compared the differences between medical and nonmedical students. It was a cross-sectional study using self-administered anonymous questionnaires. Nine-hundred sixty full-time college students were recruited randomly at Peking University in China. The medical students had higher level of knowledge of HPV and its vaccine than the nonmedical students (p < 0.001). The vaccinated female students were 9.0%. The high-grade clinical students had a higher uptake rate than the nonmedical students (19.5 vs 8.6%, p < 0.05). Awareness of HPV (p < 0.01), awareness of the vaccine (p < 0.001), and vaccinated family members or friends (p < 0.001) were related to the nonmedical students' vaccination. Vaccinated family members or friends were significant predictor for students' vaccination status (p < 0.001). Medical students knew more about HPV and its vaccine than nonmedical students. Female students' vaccinated rate was low, and the high-grade clinical students had a higher uptake rate than the nonmedical students. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to evaluate the GoldenGate microarray as a diagnostic tool and to elucidate the contribution of the genes on this array to the development of both nonsyndromic and syndromic sensorineural hearing loss in China. Methods: We developed a microarray to detect 240 mutations underlying syndromic and nonsyndromic sensorineural hearing loss. The microarray was then used for analysis of 382 patients with nonsyndromic sensorineural hearing loss (including 15 patients with enlarged vestibular aqueduct syndrome), 21 patients with Waardenburg syndrome, and 60 unrelated controls. Subsequently, we analyzed the sensitivity, specificity, and reproducibility of this new approach after Sanger sequencing-based verification, and also determined the contribution of the genes on this array to the development of distinct hearing disorders. Results: The sensitivity and specificity of the microarray chip were 98.73% and 98.34%, respectively. Genetic defects were identified in 61.26% of the patients with nonsyndromic sensorineural hearing loss, and 9 causative genes were identified. The molecular etiology was confirmed in 19.05% and 46.67% of the patients with Waardenburg syndrome and enlarged vestibular aqueduct syndrome, respectively. Conclusion: Our new mutation-based microarray comprises an accurate and comprehensive genetic tool for the detection of sensorineural hearing loss. This microarray-based detection method could serve as a first-pass screening (before next-generation-sequencing screening) for deafness-causing mutations in China. [ABSTRACT FROM AUTHOR]

Although it's well known that the carbon intensity from passenger transport of cities varies widely, few studies assessed the disparities of that in city-level and its underlying factors due to the limited availability of data, and thus developed effective strategies for different types of cities. This study is the first to present a comprehensive inventory of emissions from passenger transport on road for 360 cities in mainland China for 2018, based on the data from 5 transport modes and evaluated by combining distance-based and top-down fuel-based methods. In 2018, passenger transport on road in China emitted 1076 MtC. A large portion of CO 2 emissions was identified in the southern and eastern coastal areas and capital cities. GDP, population, and policy were the major factors determining the total CO 2 emissions, but not carbon intensity. Clustering analysis of carbon intensity and 9 socio-economic predictors, using a tree-based regression model, clustered the 360 cities into 6 groups and showed that higher carbon intensities occurred in both affluent city groups with a high active population share and less affluent city groups with a low population density but high density of trip destinations. Forward-and-backward stepwise multiple regression analysis indicated that constructing a compact city is more effective for city groups with a high income and high active population share. Enhancing land-use mixed degree is more critical for city groups with a high income and low active population share, while shortening travel distance by intensifying infrastructure construction is more important for the less affluent city groups. • A new comprehensive inventory of China's city-level emissions from passenger transport on road is presented. • GDP, population, and policy were the major factors determining the total CO 2 emissions, but not carbon intensity. • The active population share and density of trip destinations have significant effect in carbon intensities. • The compactness, land-use mixed and travel distance contribute variously in different city groups. [ABSTRACT FROM AUTHOR]

Farmers and their energy saving behaviors make significant sense for long-run sustainability and enacting effective energy policies, particularly in the fragile eco-environment and non-developed rural area. This study investigates the rural household energy-saving behaviors and influencing factors in the loess hilly region of China by taking Qin'an county in Gansu province based on a total of 506 households by adopting the participatory farmer assessment method. Most peasant families pay close attention energy conservation in their daily lives. Most farmer households (88.74%) were conscious of energy saving in their daily lives, and consider energy saving as a self-acting behavior (68.58%) and good habit (87.94%); electricity is the main clean energy for farmers; the price of energy-saving products is the key factor for farmers, and the female and the younger householders have better performance in energy conservation. Farmers' energy-saving behaviors are negatively correlated with the altitude of their dwellings but positively correlated with the education level of householders, family size, income. We argue that continuous training on energy saving is necessary and should be tailored to local conditions and supported by the government. • A rural household survey of 506 households was conducted in the loess hilly region of China. • Female, younger, and higher education level shows positive impacts on energy saving. • Energy-saving behaviors positively correlated with income, health conditions, environmental concerns, and energy availability and prices. • The training efforts for promoting energy saving of rural households should be enhanced. • We argue that government subsidies should integrate into the promotion of energy-saving products. [ABSTRACT FROM AUTHOR]

New Energy Vehicles (NEVs) exert great potential in reducing carbon emissions, improving air quality and reducing the dependence on petroleum products, and are also essential in realizing the social transformation toward a low-carbon society. Since public are the principal users and stakeholders of NEVs, it's vital to understand their acceptance of NEVs and discuss the influencing factors of public acceptance, so as to promote the development of NEVs. Based on the survey data of Gansu Province, this paper analyzes the public perception and acceptance of NEVs in underdeveloped regions, and explores main factors affecting their acceptance by adopting Structural Equation Model. The results show that the public acceptance of NEVs is relatively higher, with only 51.99% residents are willing to accept NEVs. And there are differences of public acceptance of NEVs among different groups. The acceptance of females, young and less educated public are relatively higher, decreases with aging and increases with education attainment. Perceived risk and perceived cost are significantly negative correlated with public acceptance of NEVs, while subjective norm and the quality of NEVs positively correlated with public acceptance. In addition, support policy is significantly positively correlated with perceived cost while perceived cost is positively corelated with perceived risk. Finally, this paper proposes countermeasures and suggestions on improving the public acceptance of NEVs in underdeveloped regions. • We conducted the NEVs acceptance of 1356 residents in Chinese underdeveloped regions. • 51.99% of the public in underdeveloped regions of China were willing to accept NEVs. • Perceived risk, perceived cost, and NEVs' quality are the key influencing factors. • Support policy, knowledge have significant indirect impact on acceptance of NEVs. • Enhancing subsidies and supporting facilities were effective ways. [ABSTRACT FROM AUTHOR]

• We evaluate the implementation and potential impact of solar energy-based poverty reduction program in Qinghai, China. • PV stations, precisely planned to fulfill 'targeted' intervention, were aggregated into larger PV farms in implementation. • It is challenging to precisely target the poor, improve income, facilitate energy transition, and enhance local capacity. • Future energy-based development needs to sufficiently consider local contexts and promote local engagement. In 2014, China initiated a nationwide poverty reduction campaign through deploying photovoltaic (PV) systems in its vast rural areas, which aims to support over 2 million households. Despite the significant socioeconomic benefits anticipated by policy-makers, it remains unclear regarding the challenges of implementing such an ambitious program in remote rural areas and its effect on poverty reduction. Focusing on Qinghai, a province that serves as the testbed for solar energy development in China but suffers chronic poverty, we aim to assess implementation status of the program, and examine whether and how solar energy-based development affects rural household well-being and generates socioeconomic spillovers. Using data from multiple sources, including household survey, interviews, policy documents, and large-scale socioeconomic covariates, as well as advanced statistical and spatial analyses, we find there have been substantial adjustments to the plan of building small-scale PV stations across poor villages throughout Qinghai. While total installation capacity was met, the 97 planned PV stations in 39 counties were aggregated into 24 medium- to large-scale PV farms in 27 counties. We also find substantial challenges to precisely target the poor, improve their income, facilitate a transition in household use of energy, and enhance local capacity for economic development. Future PV-based intervention programs need to sufficiently consider local contexts and demands, and promote local engagement to achieve the twin goals of sustainable energy transition and poverty reduction. [ABSTRACT FROM AUTHOR]