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[Objective] To explore the contents of liquiritin and glycyrrhizic acid in different medicinal parts and growth years of Glycyrrhiza uralensis in Korla, Bayingol Mongolia Autonomous Prefecture, Xinjiang, so as to provide basis for effective quality control. [Method] Taking the active components liquiritin and glycyrrhizic acid in Glycyrrhiza uralensis stipulated in the 2020 edition of Pharmacopoeia of the People's Republic of China as the detection standard, the contents of liquiritin and glycyrrhizic acid in different medicinal parts and growth years of Glycyrrhiza uralensis in Korla, Bayingol Mongolia Autonomous Prefecture of Xinjiang were determined and compared by HPLC, and the quality of traditional Chinese medicine was discussed from the point of view of chemical composition. [Result] The order of the content of liquiritin and glycyrrhizic acid in various medicinal parts of licorice was lateral root>main root>whole root>floating root>fibrous root>reed head; the contents of liquiritin in lateral root, main root and whole root met the requirements of the Chinese Pharmacopoeia (2020 edition) (≥0.50%); the content of glycyrrhizic acid in lateral roots met the requirements of the Chinese Pharmacopoeia (2020 edition) (≥2.0%); three-year-old Glycyr- rhiza uralensis had the best quality. [Conclusion] The fibrous root directly removed in the traditional processing method can be used as the raw material for the extraction of liquiritin. This study can provide reference for the harvesting, processing and grading of licorice. [ABSTRACT FROM AUTHOR]

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