1. Orthohepadnavirus infection in a neotropical bat (Platyrrhinus lineatus).
- Author
-
de Souza AJS, Malheiros AP, Chagas AACD, Paiva VLGDS, Lauri LS, Scheffer KC, Mori E, Gomes-Gouvêa MS, Pinho JRR, and Sá LRM
- Subjects
- Animals, Brazil epidemiology, Hepatitis B virus, Phylogeny, Chiroptera, Orthohepadnavirus
- Abstract
Hepatitis B virus (HBV) is the prototype of the Orthohepadnavirus genus and represents an important cause of chronic hepatitis, liver cirrhosis, and hepatic cancer in humans worldwide. To verify the occurrence and genetic variability of orthohepadnavirus among neotropical bats, we tested 81 liver samples of New World bats from São Paulo State, Southeastern Brazil, collected during 2012. PCR, sequencing, and phylogenetic analysis of Surface/Polymerase and Core viral genes confirmed the occurrence of the first isolate of bat orthohepadnavirus detected in South America. These results may contribute to subsequent studies of the origin, variability, host species, and evolution of bat orthohepadnaviruses in South America., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF