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Wound healing is a complex, dynamic and difficult process. Much effort and attempt has been made to accelerate this process. The purpose of this study is to prepare nanoparticles loaded with vaccarin (VAC-NPS)hydrogel and evaluate its effect on promoting wound healing. In the present study, the physicochemical properties of VAC-NPS were characterized. Transmission electron microscopy (TEM) was used to observe the morphology of VAC-NPS. Human umbilical vein endothelial cells (HUVEC) was employed to assessment the biocompatibility of VAC-NPS in vitro. The wound healing function of VAC-NPS hydrogels was evaluated in the full-thickness dermal wound in a rat model. The results indicated that VAC-NPS was spherical like particles with uniform particle size distribution and no obvious aggregation with a diameter of (216.6 ± 10.1)nm. The loading capacity and encapsulation efficiency of VAC in the nanoparticles were (14.3 ± 1.2) % and (51.7 ± 1.7) % respectively. MTT assay demonstrated that the VAC-NPS had no cytotoxicity and could promote HUVEC proliferation and migration. In vivo results showed that VAC-NPS promotes wound healing, and the mechanism may be through up-regulating IL-1β and PDGF-BB, promoting angiogenesis. VAC-NPS might have a potential application value for the treatment of the wound healing and a promising performance in bio-medically relevant systems., Competing Interests: Declaration of competing interest There are no conflicts to declare., (Copyright © 2020. Published by Elsevier B.V.)

Chitosan nanoparticles (chitosan NP) were effectively incorporated onto cotton fiber surfaces during a green adsorption without any cross-linking agents in this work. The interactions between cotton fibers and chitosan NP during the green adsorption were investigated by Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), thermogravimetric-derivative thermogravimetry (TG-DTG) and scanning electron microscopy (SEM) in detail. The results indicated that the intermolecular hydrogen bond interactions exited between the hydroxyl groups of cotton fibers and the amino groups of chitosan NP, and progressively enhanced with the increase in chitosan NP mass concentrations. After chitosan NP adsorption, the acidity of fibers augmented and the crystallinity index of fibers declined owing to the increasing interactions. In addition, the hydrophobic interactions occurred between chitosan NP and crystalline cotton fibers, thereby resulting in the preferential adsorption onto the hydrophobic (200) crystallographic plane., (Copyright © 2013 Elsevier Ltd. All rights reserved.)

The stable adsorption of chitosan nanoparticles (CNs) onto cotton fabrics was successfully developed without any chemical binders. The adsorption kinetics, thermodynamics, and capacities under different experimental conditions were investigated. The structure and laundering durability of CNs-adsorbed cotton fabrics (CNs-cotton) were also characterized by Scanning Electron Microscope (SEM), Fourier Transform Infrared Spectroscopy (FTIR), X-ray Photoelectron Spectroscopy (XPS), and Thermo Gravimetric Analysis (TGA). The adsorption capacities of cotton for CNs declined with the increasing CNs particle size and temperature. By contrast, adsorption capacities increased with the increasing adsorption pH and CNs mass concentration. The kinetic adsorption of CNs onto cotton fabrics was found to follow the pseudo-second-order kinetic model. The adsorption mechanism reflected a complex process, and the intra-particle diffusion was not the only rate-limiting step. The transfer and diffusion rates progressively increased with the decrease of adsorption temperature and CNs particle size. The negative values of the standard Gibbs free energy changes (Δ G°) and the standard enthalpy (Δ H°) indicated that the adsorption was exothermic and spontaneous at 5-75°C. The superior laundering resistance of CNs-cotton was demonstrated after 30 consecutive washes, thereby proving the stable adsorption of CNs onto cotton fabrics without chemical binders. POLYM. COMPOS., 36:2093-2102, 2015. © 2014 Society of Plastics Engineer [ABSTRACT FROM AUTHOR]

Chitosan nanoparticles loaded with cinnamon essential oil (CE-NPs) exhibited the excellent antimicrobial and antioxidant property for the pork during refrigerated storage. In this study, CE-NPs with three sizes of 112 nm, 215 nm and 527 nm were prepared by ionic gelification reaction. The loading capacity of cinnamon essential oil was improved with the mean diameter of CE-NPs increasing. The fresh pork was wrapped with the low density polyethylene (LDPE) films and the active films coated with different CE-NPs and displayed at 4 °C for 15 day. The active films with 527 nm CE-NPs led to a significant decrease of microbial growth, pH, peroxide value (POV), 2-thiobarbituric acid (TBA) and sensory scores of the pork ( P < 0.05) than the other treatments at the end of storage. The 527 nm-treated pork samples showed significantly highest redness ( P < 0.001) in all the four groups. In all, CE-NPs with the big size have more potential as a natural preservative to maintain the quality of meat and meat products. [ABSTRACT FROM AUTHOR]

Osmanthus fragrance-loaded chitosan nanoparticles (OF-NPs) were prepared via complex coacervation successfully. Then, the OF-NPs were applied in the cotton fabrics directly. The microstructures of OF-NPs were characterized by dynamic light scattering (DLS), transmission electron microscopy (TEM), Fourier transformation infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). The sustained property of the cotton fabrics treated with OF-NPs was investigated with scanning electron microscopy (SEM) and gas chromatography-mass spectrometry (GC-MS). The common OF was also treated on fabrics for the parallel comparison. TEM and DLS displayed that the spherical OF-NPs kept about 130 nm and dispersed evenly. FTIR confirmed that OF had been interacted with chitosan via the hydrogen bonds. TGA demonstrated that the thermal stability of OF-NPs had been improved in contrast to OF and the loading content of OF was as high as 12.05%. SEM and GC-MS displayed that the cotton fabrics treated by OF-NPs had an excellent washing resistance. Overall, nanoencapsulation with CS-TPP will provide an excellent method for releasing fragrance. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012 [ABSTRACT FROM AUTHOR]

The long-term fragrance releasing textiles hold considerable market share in textile consumption market. Then, encapsulating fragrance in nanoparticles could reduce the evaporation of volatile components and prolong the service life of aroma finished textiles. In this paper, chitosan (CS) with excellent biocompatibility and biodegradability was used to encapsulate rose fragrance to form nanoparticles via the ionic gelification. The mean diameter of spherical chitosan nanoparticles loaded with fragrance (RF-NPs) was 138 nm, zeta potential was 10.20 mV and polydispersity index (PDI) was 0.110. RF-NPs and compounded rose fragrance (RF) were applied to the cotton fabrics respectively without the adhesive agents. Scanning electron microscopy (SEM) demonstrated that the number of the fragrance particles on the cotton fibres finished by RF-NPs was more than that finished by RF. Besides, after 20 cycles of washing, more RF-NPs still fixed on the surface of the cotton fabrics. Fourier transform infrared spectrometry (FT-IR) proved that RF-NPs have been incorporated into the cotton fibres successfully. Gas chromatography-mass spectrometry (GC-MS) analysis and ultraviolet (UV) spectrum analysis showed that the fragrance loss from the cotton fabrics finished by RF-NPs was obviously lower than that by RF after 20 washing cycles. The cotton fabrics finished by chitosan nanoparticles loaded with fragrance had better sustained release property, which provided a preparation method of the green aroma fnished textiles without the resin. [ABSTRACT FROM PUBLISHER]

Citronellol (CI)-loaded, chitosan (CS)-enclosed dendritic mesoporous organosilica nanoparticles (CI@D-MONs@CS) are successfully fabricated. The synthesized CI@D-MONs@CS present spherical shape with the particle size of 424±24 nm in diameter and dendritic mesopores. CI loading ratio of CI@D-MONs@CS is about 12.42% from TGA analysis. CI release from CI@D-MONs@CS exhibits pH-redox dual responsiveness. More interesting, the axillary deodorant effect is investigated with Staphylococcus haemolyticus in an artificial sweat model. The results show that CI@D-MONs@CS present an excellent bacteria-killing effect and the smell of artificial sweat is greatly improved, avoiding the formation of undesirable odorant compounds from the bacteria. The obtained CI@D-MONs@CS is a potential carrier of natural fragrance or actives with dual responsive release. The application of CI@D-MONs@CS is a new and effective strategy to the axillary odor problem. • The pH-redox dual responsive nanoparticles CI@D-MONs@CS were designed and fabricated. • Chitosan formed the pH-responsive "gate" of CI@D-MONs@CS. • CI@D-MONs@CS exhibited significantly enhanced and durable antibacterial capacities. • CI@D-MONs@CS greatly reduced the off-odor caused by the axillary bacteria. • Application of CI@D-MONs@CS was a new and effective strategy to the axillary odor problem. [ABSTRACT FROM AUTHOR]