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Hernias and abdominal wall defects are routinely treated using synthetic and biological meshes. However, complications such as hernia recurrence and seroma and adhesion formation are quite common. So far, various materials have been employed to prevent adhesions while ensuring good mechanical properties. A good hernia mesh should harbor outstanding parietal surface tissue in-growth with minimal visceral surface adhesiveness. A good way to minimize the disadvantages of surgical meshes is to combine synthetic and natural polymers to ensure adequate biomechanical properties, or to design innovative meshes that can replace current hernia meshes. In this study, we have designed polyester (PES) meshes impregnated with chitosan that exhibited increased biocompatibility. These preliminary results pave the way for future ex vivo and in vivo studies.

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The scope of this article is to develop composite membranes using chitosan (CS) and graphene oxide (GO) as adsorbents for the removal of inorganic pollutants such as heavy metal ions, particularly Pb2+, from aqueous solutions. GO was obtained by modified Hummers method and blended with CS solution. The introduction of ethylenediaminetetraacetic acid (EDTA) compound to CS/GO suspension lead to an increased adsorption capacity of CS/GO for the elimination of heavy metals by forming stable chelates with them. The synthesized membranes were examined by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM), and the adsorption behaviour of Pb2+ from aqueous solutions using CS/EDTA/GO membranes was evaluated using inductively coupled plasma mass spectrometry (ICP-MS). The adsorption performance of Pb2+ ions was studied by monitoring the concentration of Pb2+ against the adsorption period at an initial content of the adsorbent. The maximum adsorption efficiency of Pb2+ metal ions reached 767 mg·g−1 for CS/EDTA/GO 0.1%, 889 mg·g−1 for CS/EDTA/GO 0.3%, 970 mg·g−1 for CS/EDTA, 853 mg·g−1 for CS and 1526 mg·g−1 for GO. These findings show promising potential for CS/EDTA/GO membranes as effective adsorbent materials for the removal of heavy metal ions in water. [ABSTRACT FROM AUTHOR]