1. Effect of pre-operative opioid exposure on surgical outcomes in elective laparoscopic cholecystectomy.
- Author
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Perlmutter B, Wynia E, McMichael J, Tu C, Scheman J, Simon R, Walsh RM, and Augustin T
- Subjects
- Elective Surgical Procedures, Humans, Length of Stay, Treatment Outcome, Analgesics, Opioid therapeutic use, Cholecystectomy, Laparoscopic adverse effects
- Abstract
Background: The effects of varying levels of pre-operative opioids on post-operative outcomes following elective laparoscopic cholecystectomy is largely unknown., Methods: Patients who underwent elective laparoscopic cholecystectomy from 2012 to 2019 were reviewed and categorized by the number of outpatient opioid prescriptions received in the 90 days preceding surgery: none (Naïve), one (1 Rx), two (2 Rx), or three or more (Chronic). Operative time, hospital length of stay, and 30-day readmission rate were analyzed., Results: Of the 11911 patients identified, 2958 (24.8%) used opioids pre-operatively. Among patients with an overnight admission, the Naïve, 1 Rx, and 2 Rx cohorts had a shorter length of stay compared to the Chronic cohort. The Naïve group had the lowest 30-day readmission rate (5.0%) followed by the 1 Rx (5.9%), 2 Rx and Chronic groups (9.1% and 8.7%, respectively) (p < 0.001)., Conclusions: Prevalence of pre-operative opioid use is high and warrants surgeon assessment to minimize adverse post-operative outcomes., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2022
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