1. Measuring Chromatin Accessibility: ATAC-Seq.
- Author
-
Sahu SK, Basu A, and Tiwari VK
- Subjects
- Computational Biology methods, DNA Transposable Elements, Data Analysis, Gene Expression Regulation, Gene Library, Genome-Wide Association Study, Humans, Nucleosomes metabolism, Quality Control, Sequence Analysis, DNA, Transposases metabolism, Chromatin genetics, Chromatin Assembly and Disassembly, High-Throughput Nucleotide Sequencing methods
- Abstract
Assay for Transposase-Accessible Chromatin using sequencing (ATAC-Seq) is a method to investigate the accessibility of chromatin in a genome-wide fashion. In this chapter, we provide a brief history of the chromatin accessibility field followed by a detailed protocol to perform ATAC-Seq assay., (© 2021. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2021
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