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To study the process conditions for preparing aspirin β-cyclodextrin inclusion.Method: Choose the usage ration of aspirin with β-cyclodextrin and the time of reaction as the main factors, and use the inclusion yield as evaluated indicators and the process condition to conduct orthogonal experiment Optimization Pack aspirin.Outcome: The optimum inclusion process condition: molar ratio of the aspirin with β-cyclodextrin is 1:3, inclusion time is 60 minutes.Conclusion: The process condition of using β-cyclodextrin inclusion to inconcluse aspirin is feasible, effective, and of applicative value.

To study the process conditions for preparing sultamicillin tosilate β-cyclodextrin inclusion.Method: Choose the usage ration of sultamicillin tosilate with β-cyclodextrin, the inclusion temperature and the time of reaction as the main factors, and use the inclusion yield as evaluated indicators and the process condition to conduct the L9 (34) orthogonal experiment Optimization Pack sultamicillin tosilate.Outcome: The optimum inclusion process condition: molar ratio of the sultamicillin tosilate with β-cyclodextrin is 1:8, inclusion temperature is 47°C, inclusion time is 40 minutes.Conclusion: The process condition of using β-cyclodextrin inclusion to inconcluse sultamicillin tosilate is feasible, effective, and of applicative value.

Although Apocynum leaves have been used for the treatment of cardiovascular diseases, the study on active compounds of Apocynum venetum L. is little. In this paper,high performance liquid chromatography with mass spectrometry (HPLC-MS) were used for the active ingredient in qualitative analysis of Apocynum leaves, based on the information of the mass spectrum molecular ion peak [M-and some characteristic fragment ions, and combined with UV spectral characteristics we initially speculated that Apocynum leaves water extract isolated to 10 components.