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Start Over Author "Miyosi, O." Topic chromosomes, human, pair 19

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1. The human gene encoding the heavy chain of the major histocompatibility complex class I-like Fc receptor (FCGRT) maps to 19q13.3.

Author

Kandil E, Egashira M, Miyoshi O, Niikawa N, Ishibashi T, and Kasahara M

Subjects
Animals, Chromosome Mapping, DNA, Complementary genetics, Gene Library, Genes, Histocompatibility Antigens Class I chemistry, Humans, In Situ Hybridization, Fluorescence, Major Histocompatibility Complex, Mice, Receptors, Fc chemistry, Species Specificity, Chromosomes, Human, Pair 19 genetics, Receptors, Fc genetics
Abstract

FcRn is an Fc receptor that structurally resembles the major histocompatibility complex class I molecule. In this study, we isolated the human gene encoding the heavy chain of FcRn (FCGRT) and mapped it by fluorescence in situ hybridization to chromosome band 19q13.3. Thus, like its mouse counterpart, the human FCGRT gene is located outside the major histocompatibility complex.

Published
1996
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