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1. Update on APPEAL, an International Randomized Controlled Trial Evaluating Ciprofloxacin Versus Placebo in Patients Undergoing Shockwave Lithotripsy for Urolithiasis.

Author

Tikkinen KAO, Tornberg SV, Ruotsalainen J, Tadayon Najafabadi B, Horstia S, Hajebrahimi S, Mikkola A, Abdelkareem M, Richard PO, Bausch K, Parpia S, Guyatt GH, and Violette PD

Subjects
Humans, Anti-Bacterial Agents therapeutic use, Antibiotic Prophylaxis, Urinary Tract Infections prevention & control, Ciprofloxacin therapeutic use, Lithotripsy methods, Lithotripsy adverse effects, Randomized Controlled Trials as Topic, Urolithiasis therapy
Abstract

The blinded APPEAL trial is assessing the effectiveness of antimicrobial prophylaxis in preventing infections after shockwave lithotripsy for urinary stones. This large, pragmatic, international trial will provide trustworthy evidence to inform guidelines and influence global practices., (Copyright © 2024 European Association of Urology. Published by Elsevier B.V. All rights reserved.)

Published
2024
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