1. Assessing the Influence of Climate on the Spatial Pattern of West Nile Virus Incidence in the United States.
- Author
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Gorris, Morgan E, Randerson, James T, Coffield, Shane R, Treseder, Kathleen K, Zender, Charles S, Xu, Chonggang, and Manore, Carrie A
- Subjects
Animals ,Humans ,West Nile virus ,West Nile Fever ,Incidence ,Canada ,United States ,Cold Temperature ,Biodefense ,West Nile Virus ,Rare Diseases ,Emerging Infectious Diseases ,Vaccine Related ,Vector-Borne Diseases ,Infectious Diseases ,Prevention ,Climate Action ,Environmental Sciences ,Medical and Health Sciences ,Toxicology - Abstract
BackgroundWest Nile virus (WNV) is the leading cause of mosquito-borne disease in humans in the United States. Since the introduction of the disease in 1999, incidence levels have stabilized in many regions, allowing for analysis of climate conditions that shape the spatial structure of disease incidence.ObjectivesOur goal was to identify the seasonal climate variables that influence the spatial extent and magnitude of WNV incidence in humans.MethodsWe developed a predictive model of contemporary mean annual WNV incidence using U.S. county-level case reports from 2005 to 2019 and seasonally averaged climate variables. We used a random forest model that had an out-of-sample model performance of R2=0.61.ResultsOur model accurately captured the V-shaped area of higher WNV incidence that extends from states on the Canadian border south through the middle of the Great Plains. It also captured a region of moderate WNV incidence in the southern Mississippi Valley. The highest levels of WNV incidence were in regions with dry and cold winters and wet and mild summers. The random forest model classified counties with average winter precipitation levels
- Published
- 2023