1. Validity and interobserver agreement of reagent strips for measurement of glucosuria
- Author
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Boudewijn J. Kollen, Jolita Bekhof, Corrie Deiman, Liesbeth J. M. Groot-Jebbink, Henrica L. M. Van Straaten, Sjef J. C. M. Van de Leur, Science in Healthy Ageing & healthcaRE (SHARE), and Life Course Epidemiology (LCE)
- Subjects
Interobserver reliability ,Urinalysis ,Clinical Biochemistry ,Analytical chemistry ,INFANTS ,Clinical settings ,Urine ,interobserver reliability ,Test strips ,dipsticks ,URINALYSIS ,Glycosuria ,Medicine ,Humans ,glucose ,Reagent Strips ,Observer Variation ,Chromatography ,Reagent strip ,medicine.diagnostic_test ,glucosticks ,business.industry ,General Medicine ,Precision ,Reagent ,RELIABILITY ,business - Abstract
Background. Measurement of glucosuria by means of a visually readable reagent test strip is frequently used in a wide variety of clinical settings. The aim of this study was to evaluate the validity and reliability of this semi-quantitative measurement of glucosuria compared to laboratory measurements of glucose concentrations in urine. Methods. Reagent test strips (Combur(3)Test (R) Roche) from 375 artificially supplemented samples of urine, covering a wide range of glucose concentrations, were independently read by three different observers. Scores of the strips were categorized as 0, 1+, 2+, 3+ or 4+, in ascending degree of glucosuria. Results of the test-strips were compared to the quantitative measurement of urinary glucose concentration in the laboratory. Results. 21.7% of reagent strips readings were discordant with the laboratory measurements ( p
- Published
- 2011