1. Urinary neonicotinoid insecticides in children from South China: Concentrations, profiles and influencing factors.
- Author
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Zhao, Yang, Zhu, Zhou, Xiao, Qinru, Li, Zihan, Jia, Xiaohong, Hu, Wanting, Liu, Kuancheng, and Lu, Shaoyou
- Subjects
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THIAMETHOXAM , *INSECTICIDES , *IMIDACLOPRID , *NEONICOTINOIDS , *NICOTINIC acetylcholine receptors , *THIACLOPRID , *CLOTHIANIDIN - Abstract
Neonicotinoid insecticides can selectively interact with the unique nicotinic acetylcholine receptor subtypes in insects and are considered to be low toxic to mammals. However, there is still insufficient knowledge on human exposure to neonicotinoid insecticides, especially for children. This study aimed to investigate urinary concentrations and profiles of neonicotinoid insecticides in South China children and to analyze potential influencing factors. Six neonicotinoid insecticides, including imidacloprid (IMI), thiamethoxam (THM), acetamiprid (ACE), clothianidin (CLO), thiacloprid (THD) and dinotefuran (DIN), exhibited high detection frequencies (>90%) in urine samples collected from 305 children, suggesting broad exposure in South China children. The median concentrations were determined to be 0.13, 0.21, 0.01, 0.19, 0.002 and 1.64 μg/L, respectively. Among the target neonicotinoids, urinary concentrations of CLO and THM exhibited a significant and positive correlation between each other (p < 0.05), suggesting similar sources of these two chemicals. [Display omitted] • Neonicotinoid insecticides were frequently detected in urine samples from South China children. • DIN was the most abundant neonicotinoid insecticide in urine samples. • Urinary CLO positively correlated with THM, indicating similar exposure sources. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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