Linsey C. Marr, Miguela A. Caniza, Hong Kai Lee, Alejandra Nava Ruiz, Yuguo Li, Julian Tang, Chun Kiat Lee, Carlos Francisco Santillan-Salas, Jean-Michel Heraud, Jin Pan, Evelyn Siew-Chuan Koay, Virginia Tech [Blacksburg], University of Leicester, St Jude Children's Research Hospital, Unité de Virologie [Antananarivo, Madagascar] (IPM), Institut Pasteur de Madagascar, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), National University of Singapore (NUS), Agency for science, technology and research [Singapore] (A*STAR), National University Health System [Singapore] (NUHS), The University of Hong Kong (HKU), Hospital de Especialidades Pediátricas, Instituto Nacional de Salud del Niño San Borja, This research was supported by a grant from the Alfred P. Sloan Foundation as part of its Microbiology of the Built Environment program. The authors thank Kaisen Lin for helpful discussions, Julia Gohlke, Archit Manuja, and AJ Prussin II for handling sensors, and and the reviewers for their detailed feedback that helped strengthen this paper.
Posté sur engrXiv le 13 juin 2021.; The incidence of several respiratory viral infections has been shown to be related to climate. Because humans spend most of their time indoors, measures of indoor climate, rather than outdoor climate, may be better predictors of disease incidence and transmission. Therefore, understanding the relationship between indoor and outdoor climate will help illuminate their influence on the seasonality of diseases caused by respiratory viruses. Indoor-outdoor relationships between temperature and humidity have been documented in temperate regions, but little information is available for tropical regions, where seasonal patterns of respiratory viral diseases differ. We have examined indoor-outdoor correlations of temperature, relative humidity (RH), and absolute humidity (AH) over a 1-year period in each of seven tropical cities. Across all cities, the average monthly indoor temperature was 25±3°C (mean ± standard deviation) with a range of 20–30°C. The average monthly indoor RH was 669% with a range of 50–78%, and the average monthly indoor AH was 153 g/m3 with a range of 10–23 g/m3. Indoor AH and RH were linearly correlated with outdoor AH when the air-conditioning (AC) was off, suggesting that outdoor AH may be a good proxy of indoor humidity in the absence of AC. All indoor measurements were more strongly correlated with outdoor measurements as distance from the equator increased. Such correlations were weaker during the wet season, especially when AC was in operation. These correlations will provide insight for assessing the seasonality of respiratory viral infections using outdoor climate data, which is more widely available than indoor data, even though transmission of these diseases mainly occurs indoors.