Introduction: Epilepsy is among the main existing neurological diseases. Caregivers of children and adolescents can influence the dietary pattern of their dependents, through their food choices, and change the frequency of epileptic seizures and the clinical status. Objective: This study aims to assess the correlation between the sociodemographic profile, the frequency of seizures in children and adolescents with epilepsy, and the reason for their caregivers' food choices. Materials and Methods: Forty-two caregivers of children and adolescents with epilepsy were interviewed in the waiting room of an outpatient clinic of a public hospital in northern Brazil. All agreed to participate in the research (signed the consent form) and were submitted to an interview with the application of a sociodemographic and clinical questionnaire, and the Food Choice Questionnaire. Results: The food choice factor "Convenience" was the most important chosen by caregivers, followed by the factors "Sensory appeal", "Health", "Price" and "Weight control". Positive correlations were found between the dependent's age and the factors "Weight control" and family income and negative correlations between the frequency of crises seizures and the factors "Sensory appeal" and caregiver's age. Conclusion: This study showed the main reasons for food choices by caregivers of dependents with epilepsy, which were correlated with age and seizure frequency, suggesting the need to ensure food and nutrition education for caregivers and dependents in order to ensure better clinical outcomes. [ABSTRACT FROM AUTHOR]