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Background: This study aimed to evaluate the characteristics of incidental findings (IFs) on computed tomography (CT) scans of trauma admissions, examine associations between IFs and gender and age-groups, and discuss the management strategies. Methods: The CT reports were retrospectively reviewed to evaluate IFs. Cases were divided into five age-groups (0--19, 20--39, 40--59, 60--79, ≥ 80). IFs were classified as "Group 1": congenital anomalies that do not require further investigation, nondegenerative/minor degenerative findings; "Group 2": findings that do not require immediate intervention, require outpatient follow-up/in case of symptoms; and "Group 3": findings that require immediate intervention/further investigation. Results: There were 2385 CT scans and 1802 incidental findings (IFs) in 783 trauma cases. CT scans with IFs constituted 50.2%. The percentage of IFs was 75.6% in males and 24.4% in females, and they occurred in 4.8%, 27.6%, 44.3%, 20.9%, and 2.4% of age groups 1 to 5, respectively. Group 1 had 34.6%, group 2 had 54.6%, and group 3 had 10.8% IFs. There was not any significant association between the classification and gender or age-groups. In terms of organs, IFs of the thyroid and gall bladder & bile ducts were significantly higher among females (P = 0.044 and P < 0.001, respectively), while IFs in the head & neck region were significantly higher in males (P < 0.001). Incidental findings in the kidney, liver, adrenal gland, and vascular structures differed significantly across age-groups (P < 0.05). Conclusion: There were no significant relationships between the classification of IFs and gender or age-groups. However, the distribution of IFs was significantly associated with gender and age-groups in terms of organs. Healthcare professionals should consider this relationship when following up and treating patients. [ABSTRACT FROM AUTHOR]

The article describes the case of a 70-year-old male diagnosed with primary tuberculosis (TB) of the thyroid gland. The patient presented with a large fluctuating right neck mass present for the previous 4 months. Topics covered include the findings of the contrast enhanced compute tomography of the neck, the treatment given to the patient and the variability of the presentation of the primary thyroid TB.

Background: Thyroid ultrasound has undergone a dramatic transformation from the cryptic deflections on an oscilloscope produced in A-mode scanning, to barely recognizable B-mode images, followed by initial low resolution gray scale, and now modern high resolution images. Aim: The aim of the present study was to evaluate the diagnostic role of ultrasonography (USG) and multi-detector computed tomography (MDCT) in thyroid swellings, compare the ultrasonographic findings with multi-detector computed tomographic findings and to correlate the radiological findings with histopathological examination (HPE). Materials and methods: The present study was carried out in the Department of Radiology, Kamineni Institute of Medical Sciences, Narketpally. In this study, 50 patients with thyroid gland swellings diagnosed clinically, referred to Radiology Department were selected during the period from October 2008 to September 2010. Histopathological examination was acquired in 35 cases. The study was carried out to observe the sensitivity, specificity and diagnostic accuracy of USG and MDCT in thyroid gland swellings. Results: Maximum number of patients belonged to the age group of 21-40 years that was 27 cases (54.00%) and maximum number of patients were females - 41 cases (82.00%). Most common diagnosis was multi-nodular goitre on USG-16 cases (32.00%) and MDCT-14 cases (28.00%), solitary thyroid nodule is common in the right lobe of thyroid by USG-5 cases (62.50%) and MDCT-5 cases (62.50%). Most common malignancy was papillary carcinoma of thyroid-5 cases (62.50%) and most common inflammatory disorder was hashimoto's thyroiditis-5 cases (10.00%). Conclusion: The present study has concluded that USG is the fast and cost-effective modality of imaging investigation of choice in thyroid diseases and for differential diagnosis of thyroid nodules. MDCT is superior to ultrasound in evaluating retrosternal extension, relations and infiltrations in large lesions. It is also very helpful in evaluating extra-capsular, mediastinal, vascular invasion, lymph nodal involvement and metastasis. MDCT is very crucial in preoperative planning in malignancies of thyroid and large benign lesions. [ABSTRACT FROM AUTHOR]

Purpose This study aims to establish normative reference values for thoracic aortic diameter (AD) in participants in the National Lung Screening Trial. Methods Thoracic AD on 322 prevalence computed tomography was recorded at the sinotubular junction, mid-ascending, transverse arch, mid-descending, and diaphragmatic hiatus. Results Mean AD (cm) and upper limits of normal for men and women were recorded for at each location. Smoking did not correlate with AD. Age, gender, and body surface area (BSA) were the most significant factors. Conclusions Thoracic AD reference values are reported. They do not correlate with smoking, but they did for age, gender, and BSA. [ABSTRACT FROM AUTHOR]

Background: No previous study has investigated computed tomography (CT) features of benign and malignant solid thyroid nodules using detailed CT features and histopathological results.Purpose: To assess CT features of benign and malignant solid thyroid nodules in patients who underwent thyroid surgery.Material and Methods: From January to April 2014, 151 consecutive patients underwent neck CT before thyroid surgery. In each case, neck CT was retrospectively examined by a single radiologist. We evaluated the diagnostic accuracy of specific CT features for differentiating malignant from benign thyroid nodules using histopathological results as a reference standard.Results: Of 173 thyroid nodules in 142 patients, 162 (mean diameter, 12.8 ± 10.3 mm; range, 5.0-93.7 mm) were visualized on neck CT. Of 162 nodules in 133 patients, 116 were malignant and 46 were benign as confirmed by histopathology. A multivariate logistic regression analysis showed a significant difference between malignant and benign thyroid nodules in the degree and pattern of nodular enhancement, but there were no significant differences in other CT features. In particular, thyroid nodules with exophytic configuration, irregular margin, taller-than-wide shape, punctate calcifications, or homogeneously decreased enhancement showed a high malignancy rate.Conclusion: The study demonstrated that the degree and pattern of nodular enhancement are helpful CT features for differentiating malignant from benign solid thyroid nodules. [ABSTRACT FROM AUTHOR]

• Multi-classifying thyroid disease leads to enhanced diagnostic decision-making. • Ultrasound image modalities outperform CT scans regarding CAD detection. • Xception generalizes well to different medical image modalities. • Adoptions of CAD in the clinic need to earn confidence among doctors and patients. [Display omitted] Background and Objective: As one of the largest endocrine organs in the human body, the thyroid gland regulates daily metabolism. Early detection of thyroid disease leads to reduced mortality rates. The diagnosis of thyroid disease is usually made by radiologists and pathologists, which heavily relies on their experience and expertise. To mitigate human false-positive diagnostic rates, this paper proves that deep learning-driven techniques yield promising performance for automatic detection of thyroid diseases which offers clinicians assistance regarding diagnostic decision-making. Method: This research study is the first of its kind, which adopts two pre-operative medical image modalities for multi-classifying thyroid disease types (i.e., normal, thyroiditis, cystic, multi-nodular goiter, adenoma, and cancer). Using the current state-of-the-art performing deep convolutional neural network (CNN) architecture, this study builds a thyroid disease diagnostic model for distinguishing among the disease types. Results: The model obtains unprecedented performance for both medical image sets, and it reaches an accuracy of 0.972 and 0.942 for ultrasound images and computed tomography (CT) scans correspondingly. Conclusion: The experimental results illustrate that the selected CNN can be adapted to both image modalities, indicating the feasibility of the deep learning model and emphasizing its further applications in clinics. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To quantitatively evaluate the diagnostic value of gemstone spectral CT in thyroid disease.PATIENTS and METHODS: A total of 123 patients with thyroid diseases were enrolled in the retrospective study. All the patients underwent spectral CT scan, and 39 of them underwent dual-phase enhanced scan. Iodine concentration (IC) and normalized IC (NIC) were compared between benign and malignant nodules. The optimal threshold to predict malignancy was obtained by receiver operating characteristic curve (ROC). Multivariate ROC analysis was performed to evaluate the efficacy of combining the IC (NIC) and conventional morphological characteristics.RESULTS: Ten diffuse diseases and 113 nodular diseases were confirmed by clinical laboratory examination and histopathology. In total, 122 nodules (87 benign and 35 malignant) were detected, 41 nodules in enhanced cases. The IC and NIC_{VP} of malignant nodules were significantly lower than benign nodules in noncontrast and venous phase (VP) (P=0.000). The optimal IC and NIC_{VP} threshold was 0.68 mg/mL and 0.38, achieving 74.3% and 76.9% sensitivity, 66.7% and 80.0% specificity, respectively. For multivariate analysis, the area under ROC (AUC) was 0.88 and 0.94 in noncontrast and VP, respectively. Sensitivities of 77.1% and 84.6%, and specificities of 84.5% and 88.0% were achieved. CONCLUSION: Gemstone spectral CT can generally evaluate the abnormal iodine content in thyroid disease. Lower iodine can help differentiating malignant from benign nodules. A comprehensive analysis combining spectrum parameters and morphological characteristics is suggested in differential diagnosis. [ABSTRACT FROM AUTHOR]

Abstract: The aim of this study was to compare the diagnostic values of thyroid ultrasound (US) and neck computed tomography (CT) in incidentally detecting diffuse thyroid disease (DTD). A single radiologist made US and CT diagnoses of incidentally detected DTD in 130 consecutive patients before thyroidectomy for various malignancies. Histopathologic examinations confirmed normal thyroid (n = 80), Hashimoto thyroiditis (n = 20), non-Hashimoto lymphocytic thyroiditis (n = 28) and diffuse hyperplasia (n = 2). Receiver operating characteristic curves revealed that the best diagnostic indices of both imaging methods were achieved on the basis of two or more abnormal imaging findings. The sensitivity, specificity and accuracy of US and CT in incidentally detecting DTD by this classification were 72% and 72%, 87.5% and 91.3% and 81.5% and 83.8%, respectively. Thyroid US and neck CT have similar diagnostic values for differentiating incidental DTD from normal thyroid. [Copyright &y& Elsevier]

Objective:We present a case of large, symptomatic lingual thyroid which was successfully and safely removed via a transoral approach, using the da Vinci robotic system, in an academic medical centre in Singapore.Case report:A 17-year-old female adolescent presented with a large lingual thyroid causing upper airway obstruction. She underwent robotic, minimally invasive, transoral resection using the da Vinci system. Post-operative recovery was uneventful; she was able to commence oral feeding almost immediately, and was discharged from hospital on the fourth post-operative day.Conclusion:It is surgically feasible and safe to undertake transoral robotic resection of a large lingual thyroid. This approach may allow faster recovery and shorter hospitalisation for patients. Surgical safety requires a full understanding of the intralingual neurovascular anatomy. [ABSTRACT FROM PUBLISHER]

Abstract: Objective: The purpose of this study was to evaluate the preoperative computed tomography (CT) features of thyroglossal duct cysts (TDCs), with the main purpose of evaluating criteria helpful in differentiating TDCs from other lesions in children under 10-years-of-age. Methods: A retrospective chart review was performed at Chonnam National University Hospital for the period of March 2005 to June 2011. Pediatric patients under 10-years-of-age with suspected TDCs were divided into two groups depending on their histopathologic diagnosis. Results: Of the 29 pediatric patients with suspected TDCs, 16 patients (55%) had histopathologically confirmed TDCs. Thirteen patients (45%) had dermoid cysts (n =6), ranula (n =3), and inflammatory lesions (n =4). There were no statistically significant differences between the preoperative CT findings and the final histopathologic diagnosis of TDC. There were no major complications resulting from surgical interventions. Conclusion: CT is not helpful in differentiating TDC from other lesions in children under 10-years-of-age. Therefore, we suggest that preoperative CT of suspected TDCs in children should be performed more selectively. [Copyright &y& Elsevier]

Developmental morphological abnormalities of the thyroid gland are very rare. Thyroid lobe hemiagenesis is a very rare abnormality, in which one thyroid lobe fails to develop. Ectopic thyroid is one of the common developmental anomalies of thyroid characterized by the presence of thyroid tissue in a site other than its usual. Of all, lingual thyroid is the most common manifestation of benign ectopic thyroid tissue, but it is still a rare clinical entity. Both of them seen together is even rarer. These developmental defects may or may not be associated with thyroid dysfunction. Ultrasonography (USG) is the initial modality of choice for thyroid hemiagenesis but further evaluation by computed tomography (CT) scan or nuclear scan should be done to look for other thyroid ectopic tissue rest. We report a case of right thyroid hemiagenesis with ectopic lingual thyroid in a 13-year-old female. To the best of our knowledge, only two similar cases in the world literature have been reported till date. [ABSTRACT FROM AUTHOR]

The article describes the case of a 73-year-old woman who developed intralaryngeal ectopic thyroid tissue (ETT). The patient presented with a painless mass on the right side of her neck. The ETT was found while she was undergoing evaluation for thyroid enlargement. Some theories regarding the etiology of intralaryngeal ETT are discussed.

Background: Fine-needle biopsy of the thyroid gland is the most common interventional procedure used to diagnose thyroid diseases. Serious complications are rare in this procedure. They comprise an infection with abscess formation and hemorrhage. To date, only a few case reports have described an ultrasound diagnosis of active bleeding into the thyroid gland. We established such a diagnosis using computed tomography (CT). Patient Findings: A 74-year-old woman presented to the emergency department of our hospital with complications after fine-needle biopsy of the thyroid gland. Ultrasound revealed a large hematoma surrounding the gland. A subsequent CT scan confirmed the presence of hematoma and, moreover, showed active bleeding. This finding prompted rapid surgical intervention. Conclusion: CT has the capability to show active bleeding into the thyroid gland. [ABSTRACT FROM AUTHOR]

The article describes the case of a 70-year-old woman complaining of shortness of breath due to a compressive thyroid mass that has been enlarging since 2 months prior. Computed tomography (CT) with contrast revealed an enlarged multinodular thyroid gland with moderate substernal extension and fine-needle aspiration biopsy turned out negative for malignancy. The article discusses differential diagnosis of expanding thyroid mass and the immunoglobulin G4 (IgG4)-related systemic disease (RSD).

The article presents a case study of a 67-year-old woman who underwent spontaneous remission of her large thyroid tumour. Topics discussed include the medical background of the patient, the diagnosis of her thyroid tumour, her medical examinations, her treatment, and an overview of the thyroid tumour.