1. Bayesian Fully Convolutional Networks for Brain Image Registration
- Author
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Panpan Fu, Yinghao Li, Kunpeng Cui, and Yusong Lin
- Subjects
Medicine (General) ,Source data ,Article Subject ,Computer science ,Bayesian probability ,Biomedical Engineering ,Normalization (image processing) ,Image registration ,Health Informatics ,Image processing ,02 engineering and technology ,Convolutional neural network ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,R5-920 ,0302 clinical medicine ,Medical technology ,Image Processing, Computer-Assisted ,0202 electrical engineering, electronic engineering, information engineering ,Humans ,R855-855.5 ,Transformation geometry ,business.industry ,Uncertainty ,Brain ,Bayes Theorem ,Pattern recognition ,Sensor fusion ,Magnetic Resonance Imaging ,020201 artificial intelligence & image processing ,Surgery ,Neural Networks, Computer ,Artificial intelligence ,business ,Research Article ,Biotechnology - Abstract
The purpose of medical image registration is to find geometric transformations that align two medical images so that the corresponding voxels on two images are spatially consistent. Nonrigid medical image registration is a key step in medical image processing, such as image comparison, data fusion, target recognition, and pathological change analysis. Existing registration methods only consider registration accuracy but largely neglect the uncertainty of registration results. In this work, a method based on the Bayesian fully convolutional neural network is proposed for nonrigid medical image registration. The proposed method can generate a geometric uncertainty map to calculate the uncertainty of registration results. This uncertainty can be interpreted as a confidence interval, which is essential for judging whether the source data are abnormal. Moreover, the proposed method introduces group normalization, which is conducive to the network convergence of the Bayesian neural network. Some representative learning-based image registration methods are compared with the proposed method on different image datasets. Experimental results show that the registration accuracy of the proposed method is better than that of the methods, and its antifolding performance is comparable to that of fast image registration and VoxelMorph. Furthermore, the proposed method can evaluate the uncertainty of registration results.
- Published
- 2021
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