1. Deep image prior for undersampling high-speed photoacoustic microscopy
- Author
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Laiming Jiang, Roarke Horstmeyer, Qifa Zhou, Tri Vu, Zixuan Wang, Dong Zhang, Yu Shrike Zhang, Xiaoyi Zhu, Maomao Chen, Daiwei Li, Jianwen Luo, Junjie Yao, and Anthony DiSpirito
- Subjects
FOS: Computer and information sciences ,Image quality ,Computer science ,Computer Vision and Pattern Recognition (cs.CV) ,QC1-999 ,Computer Science - Computer Vision and Pattern Recognition ,Photoacoustic microscopy ,QC221-246 ,Convolutional neural network ,02 engineering and technology ,01 natural sciences ,010309 optics ,0103 physical sciences ,FOS: Electrical engineering, electronic engineering, information engineering ,Radiology, Nuclear Medicine and imaging ,Computer vision ,High-speed imaging ,Ground truth ,Pixel ,business.industry ,Deep learning ,Physics ,Image and Video Processing (eess.IV) ,Acoustics. Sound ,Undersampling ,QC350-467 ,Electrical Engineering and Systems Science - Image and Video Processing ,Optics. Light ,021001 nanoscience & nanotechnology ,Deep image prior ,Atomic and Molecular Physics, and Optics ,Artificial intelligence ,Raster scanning ,0210 nano-technology ,business ,Raster scan ,Research Article ,Interpolation - Abstract
Photoacoustic microscopy (PAM) is an emerging imaging method combining light and sound. However, limited by the laser's repetition rate, state-of-the-art high-speed PAM technology often sacrifices spatial sampling density (i.e., undersampling) for increased imaging speed over a large field-of-view. Deep learning (DL) methods have recently been used to improve sparsely sampled PAM images; however, these methods often require time-consuming pre-training and large training dataset with ground truth. Here, we propose the use of deep image prior (DIP) to improve the image quality of undersampled PAM images. Unlike other DL approaches, DIP requires neither pre-training nor fully-sampled ground truth, enabling its flexible and fast implementation on various imaging targets. Our results have demonstrated substantial improvement in PAM images with as few as 1.4$\%$ of the fully sampled pixels on high-speed PAM. Our approach outperforms interpolation, is competitive with pre-trained supervised DL method, and is readily translated to other high-speed, undersampling imaging modalities.
- Published
- 2021