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Image fusion aims to combine information from multiple source images into a single one with more comprehensive informational content. The significant challenges for deep learning-based image fusion algorithms are the lack of a definitive ground truth as well as the corresponding distance measurement, with current manually given loss functions constrain the flexibility of model and generalizability for unified fusion tasks. To overcome these limitations, we introduce a unified image fusion framework based on meta-learning, named ReFusion, which provides a learning paradigm that obtains the optimal fusion loss for various fusion tasks based on reconstructing the source images. Compared to existing methods, ReFusion employs a parameterized loss function, dynamically adjusted by the training framework according to the specific scenario and task. ReFusion is constituted by three components: a fusion module, a loss proposal module, and a source reconstruction module. To ensure the fusion module maximally preserves the information from the source images, enabling the reconstruction of the source images from the fused image, we adopt a meta-learning strategy to train the loss proposal module using reconstruction loss. The update of the fusion module relies on the fusion loss proposed by the loss proposal module. The alternating updates of the three modules mutually facilitate each other, aiming to propose an appropriate fusion loss for different tasks and yield satisfactory fusion results. Extensive experiments demonstrate that ReFusion is capable of adapting to various tasks, including infrared-visible, medical, multi-focus, and multi-exposure image fusion. The code will be released.

Online continual learning (CL) aims to learn new knowledge and consolidate previously learned knowledge from non-stationary data streams. Due to the time-varying training setting, the model learned from a changing distribution easily forgets the previously learned knowledge and biases toward the newly received task. To address this problem, we propose a Continual Bias Adaptor (CBA) module to augment the classifier network to adapt to catastrophic distribution change during training, such that the classifier network is able to learn a stable consolidation of previously learned tasks. In the testing stage, CBA can be removed which introduces no additional computation cost and memory overhead. We theoretically reveal the reason why the proposed method can effectively alleviate catastrophic distribution shifts, and empirically demonstrate its effectiveness through extensive experiments based on four rehearsal-based baselines and three public continual learning benchmarks., Comment: Accepted by ICCV 2023

We present a virtual image refocusing method over an extended depth of field (DOF) enabled by cascaded neural networks and a double-helix point-spread function (DH-PSF). This network model, referred to as W-Net, is composed of two cascaded generator and discriminator network pairs. The first generator network learns to virtually refocus an input image onto a user-defined plane, while the second generator learns to perform a cross-modality image transformation, improving the lateral resolution of the output image. Using this W-Net model with DH-PSF engineering, we extend the DOF of a fluorescence microscope by ~20-fold. This approach can be applied to develop deep learning-enabled image reconstruction methods for localization microscopy techniques that utilize engineered PSFs to improve their imaging performance, including spatial resolution and volumetric imaging throughput., Comment: 7 Pages, 3 Figures, 1 Table

Recent deep neural networks (DNNs) can easily overfit to biased training data with noisy labels. Label correction strategy is commonly used to alleviate this issue by designing a method to identity suspected noisy labels and then correct them. Current approaches to correcting corrupted labels usually need certain pre-defined label correction rules or manually preset hyper-parameters. These fixed settings make it hard to apply in practice since the accurate label correction usually related with the concrete problem, training data and the temporal information hidden in dynamic iterations of training process. To address this issue, we propose a meta-learning model which could estimate soft labels through meta-gradient descent step under the guidance of noise-free meta data. By viewing the label correction procedure as a meta-process and using a meta-learner to automatically correct labels, we could adaptively obtain rectified soft labels iteratively according to current training problems without manually preset hyper-parameters. Besides, our method is model-agnostic and we can combine it with any other existing model with ease. Comprehensive experiments substantiate the superiority of our method in both synthetic and real-world problems with noisy labels compared with current SOTA label correction strategies., Comment: 12 pages,6 figures

To alleviate the adverse effect of rain streaks in image processing tasks, CNN-based single image rain removal methods have been recently proposed. However, the performance of these deep learning methods largely relies on the covering range of rain shapes contained in the pre-collected training rainy-clean image pairs. This makes them easily trapped into the overfitting-to-the-training-samples issue and cannot finely generalize to practical rainy images with complex and diverse rain streaks. Against this generalization issue, this study proposes a new network architecture by enforcing the output residual of the network possess intrinsic rain structures. Such a structural residual setting guarantees the rain layer extracted by the network finely comply with the prior knowledge of general rain streaks, and thus regulates sound rain shapes capable of being well extracted from rainy images in both training and predicting stages. Such a general regularization function naturally leads to both its better training accuracy and testing generalization capability even for those non-seen rain configurations. Such superiority is comprehensively substantiated by experiments implemented on synthetic and real datasets both visually and quantitatively as compared with current state-of-the-art methods.

Rain streaks might severely degenerate the performance of video/image processing tasks. The investigations on rain removal from video or a single image has thus been attracting much research attention in the field of computer vision and pattern recognition, and various methods have been proposed against this task in the recent years. However, there is still not a comprehensive survey paper to summarize current rain removal methods and fairly compare their generalization performance, and especially, still not a off-the-shelf toolkit to accumulate recent representative methods for easy performance comparison and capability evaluation. Aiming at this meaningful task, in this study we present a comprehensive review for current rain removal methods for video and a single image. Specifically, these methods are categorized into model-driven and data-driven approaches, and more elaborate branches of each approach are further introduced. Intrinsic capabilities, especially generalization, of representative state-of-the-art methods of each approach have been evaluated and analyzed by experiments implemented on synthetic and real data both visually and quantitatively. Furthermore, we release a comprehensive repository, including direct links to 74 rain removal papers, source codes of 9 methods for video rain removal and 20 ones for single image rain removal, 19 related project pages, 6 synthetic datasets and 4 real ones, and 4 commonly used image quality metrics, to facilitate reproduction and performance comparison of current existing methods for general users. Some limitations and research issues worthy to be further investigated have also been discussed for future research of this direction.

We report a framework based on a generative adversarial network (GAN) that performs high-fidelity color image reconstruction using a single hologram of a sample that is illuminated simultaneously by light at three different wavelengths. The trained network learns to eliminate missing-phase-related artifacts, and generates an accurate color transformation for the reconstructed image. Our framework is experimentally demonstrated using lung and prostate tissue sections that are labeled with different histological stains. This framework is envisaged to be applicable to point-of-care histopathology, and presents a significant improvement in the throughput of coherent microscopy systems given that only a single hologram of the specimen is required for accurate color imaging., Comment: 25 pages, 8 Figures, 2 Tables

Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes. Here we demonstrate that a deep convolutional neural network can be trained to virtually refocus a 2D fluorescence image onto user-defined 3D surfaces within the sample volume. With this data-driven computational microscopy framework, we imaged the neuron activity of a Caenorhabditis elegans worm in 3D using a time-sequence of fluorescence images acquired at a single focal plane, digitally increasing the depth-of-field of the microscope by 20-fold without any axial scanning, additional hardware, or a trade-off of imaging resolution or speed. Furthermore, we demonstrate that this learning-based approach can correct for sample drift, tilt, and other image aberrations, all digitally performed after the acquisition of a single fluorescence image. This unique framework also cross-connects different imaging modalities to each other, enabling 3D refocusing of a single wide-field fluorescence image to match confocal microscopy images acquired at different sample planes. This deep learning-based 3D image refocusing method might be transformative for imaging and tracking of 3D biological samples, especially over extended periods of time, mitigating photo-toxicity, sample drift, aberration and defocusing related challenges associated with standard 3D fluorescence microscopy techniques., Comment: 47 pages, 5 figures (main text)

We report resolution enhancement in scanning electron microscopy (SEM) images using a generative adversarial network. We demonstrate the veracity of this deep learning-based super-resolution technique by inferring unresolved features in low-resolution SEM images and comparing them with the accurately co-registered high-resolution SEM images of the same samples. Through spatial frequency analysis, we also report that our method generates images with frequency spectra matching higher resolution SEM images of the same fields-of-view. By using this technique, higher resolution SEM images can be taken faster, while also reducing both electron charging and damage to the samples., Comment: 8 pages, 4 figures

Deep learning brings bright-field microscopy contrast to holographic images of a sample volume, bridging the volumetric imaging capability of holography with the speckle- and artifact-free image contrast of bright-field incoherent microscopy., Comment: 3 pages

Holography encodes the three dimensional (3D) information of a sample in the form of an intensity-only recording. However, to decode the original sample image from its hologram(s), auto-focusing and phase-recovery are needed, which are in general cumbersome and time-consuming to digitally perform. Here we demonstrate a convolutional neural network (CNN) based approach that simultaneously performs auto-focusing and phase-recovery to significantly extend the depth-of-field (DOF) in holographic image reconstruction. For this, a CNN is trained by using pairs of randomly de-focused back-propagated holograms and their corresponding in-focus phase-recovered images. After this training phase, the CNN takes a single back-propagated hologram of a 3D sample as input to rapidly achieve phase-recovery and reconstruct an in focus image of the sample over a significantly extended DOF. This deep learning based DOF extension method is non-iterative, and significantly improves the algorithm time-complexity of holographic image reconstruction from O(nm) to O(1), where n refers to the number of individual object points or particles within the sample volume, and m represents the focusing search space within which each object point or particle needs to be individually focused. These results highlight some of the unique opportunities created by data-enabled statistical image reconstruction methods powered by machine learning, and we believe that the presented approach can be broadly applicable to computationally extend the DOF of other imaging modalities.