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Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named Medical Decision-making Agents (MDAgents) that helps address this gap by automatically assigning a collaboration structure to a team of LLMs. The assigned solo or group collaboration structure is tailored to the medical task at hand, emulating real-world medical decision-making processes adapted to tasks of varying complexities. We evaluate our framework and baseline methods using state-of-the-art LLMs across a suite of real-world medical knowledge and medical diagnosis benchmarks, including a comparison of LLMs' medical complexity classification against human physicians. MDAgents achieved the best performance in seven out of ten benchmarks on tasks requiring an understanding of medical knowledge and multi-modal reasoning, showing a significant improvement of up to 4.2% (p < 0.05) compared to previous methods' best performances. Ablation studies reveal that MDAgents effectively determines medical complexity to optimize for efficiency and accuracy across diverse medical tasks. Notably, the combination of moderator review and external medical knowledge in group collaboration resulted in an average accuracy improvement of 11.8%. Our code can be found at https://github.com/mitmedialab/MDAgents.

We describe an approach for aligning an LLM-based dialogue agent based on global (i.e., dialogue-level) rewards, while also taking into account naturally-occurring multimodal signals. At a high level, our approach (dubbed GELI) learns a local, turn-level reward model by decomposing the human-provided Global Explicit (GE) session-level reward, using Local Implicit (LI) multimodal reward signals to crossmodally shape the reward decomposition step. This decomposed reward model is then used as part of the standard RHLF pipeline improve an LLM-based dialog agent. We run quantitative and qualitative human studies to evaluate the performance of our GELI approach, and find that it shows consistent improvements across various conversational metrics compared to baseline methods., Comment: 10 pages, 3 figures, 2 tables

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the capacity of LLMs to make inferences about health based on contextual information (e.g. user demographics, health knowledge) and physiological data (e.g. resting heart rate, sleep minutes). We present a comprehensive evaluation of 12 state-of-the-art LLMs with prompting and fine-tuning techniques on four public health datasets (PMData, LifeSnaps, GLOBEM and AW_FB). Our experiments cover 10 consumer health prediction tasks in mental health, activity, metabolic, and sleep assessment. Our fine-tuned model, HealthAlpaca exhibits comparable performance to much larger models (GPT-3.5, GPT-4 and Gemini-Pro), achieving the best performance in 8 out of 10 tasks. Ablation studies highlight the effectiveness of context enhancement strategies. Notably, we observe that our context enhancement can yield up to 23.8% improvement in performance. While constructing contextually rich prompts (combining user context, health knowledge and temporal information) exhibits synergistic improvement, the inclusion of health knowledge context in prompts significantly enhances overall performance.

Accurately modeling affect dynamics, which refers to the changes and fluctuations in emotions and affective displays during human conversations, is crucial for understanding human interactions. By analyzing affect dynamics, we can gain insights into how people communicate, respond to different situations, and form relationships. However, modeling affect dynamics is challenging due to contextual factors, such as the complex and nuanced nature of interpersonal relationships, the situation, and other factors that influence affective displays. To address this challenge, we propose a Cross-person Memory Transformer (CPM-T) framework which is able to explicitly model affective dynamics (intrapersonal and interpersonal influences) by identifying verbal and non-verbal cues, and with a large language model to utilize the pre-trained knowledge and perform verbal reasoning. The CPM-T framework maintains memory modules to store and update the contexts within the conversation window, enabling the model to capture dependencies between earlier and later parts of a conversation. Additionally, our framework employs cross-modal attention to effectively align information from multi-modalities and leverage cross-person attention to align behaviors in multi-party interactions. We evaluate the effectiveness and generalizability of our approach on three publicly available datasets for joint engagement, rapport, and human beliefs prediction tasks. Remarkably, the CPM-T framework outperforms baseline models in average F1-scores by up to 7.3%, 9.3%, and 2.0% respectively. Finally, we demonstrate the importance of each component in the framework via ablation studies with respect to multimodal temporal behavior.

As we move closer to real-world AI systems, AI agents must be able to deal with multiparty (group) conversations. Recognizing and interpreting multiparty behaviors is challenging, as the system must recognize individual behavioral cues, deal with the complexity of multiple streams of data from multiple people, and recognize the subtle contingent social exchanges that take place amongst group members. To tackle this challenge, we propose the Multiparty-Transformer (Multipar-T), a transformer model for multiparty behavior modeling. The core component of our proposed approach is the Crossperson Attention, which is specifically designed to detect contingent behavior between pairs of people. We verify the effectiveness of Multipar-T on a publicly available video-based group engagement detection benchmark, where it outperforms state-of-the-art approaches in average F-1 scores by 5.2% and individual class F-1 scores by up to 10.0%. Through qualitative analysis, we show that our Crossperson Attention module is able to discover contingent behavior., Comment: 7 pages, 4 figures, IJCAI