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Aim: This study aimed at assessing the knowledge of Nigerian Ophthalmologists about computer vision syndrome. Methods: This study was conducted during the annual congress and scientific conference of the Ophthalmological Society of Nigeria which took place at Sheraton Hotels and Towers, Abuja between 16th and 18th September, 2010. One hundred and forty respondents, selected by simple random sampling, were asked to participate in this study by filling in a structured questionnaire. Informed consent was obtained from the respondents. Information obtained from the respondents with the aid of questionnaire included their bio-data, usage of computer, knowledge about computer vision syndrome, its symptoms and treatment modalities. The data obtained was collated and analyzed with SPSS 15.0.1. Results: A total of 102 filled questionnaires were retrieved out of 140 administered, giving a response rate of 73%. The respondents were comprised of 64 (62.7%) males and 38 (37.3%) females. The majority of the respondents; 27(26.5%) were consultants, 68(66.7%) were residents and 7(6.9%) were diplomates. Most respondents, 68 (66.7%) were aware of computer vision syndrome while the rest 33 (32.4%) were not aware. As detailed in Table 1, eye strain was identified as a symptom of computer vision syndrome by most respondents; 93 (91.2%). As shown in Table 2, 68 respondents agreed with the use of artificial tears in patients with computer vision syndrome. Conclusion: The majority of the respondents were aware of computer vision syndrome and had fair knowledge of its symptoms and treatment. [ABSTRACT FROM AUTHOR]