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Prosthodontic restorations made of zirconium dioxide are popular. An important step in prosthetics is the cementing of a zirconium dioxide crown on the tooth. For high-quality adhesion, the inner surface must be cleaned of saliva and blood contamination. The aim of the study is systematic review on the impact of the method on the quality of cleaning of zirconium dioxide restorations after contamination with saliva. Electronic search of articles was carried out using search engines and databases Google Scholar, Pub Med. Articles are included, the content of which relates to the topic of methods of purification of zirconium dioxide after contamination with saliva. The publication date criterion has been selected since 2013. 69 articles were reviewed during the review process. After analyzing the literature according to the inclusion criteria, the total number was 50 publications. There are many methods of cleaning zirconium dioxide from saliva contamination. There are commercial products on the dental market that show good results. Additional research methods are needed to determine the most effective method of contamination from saliva contamination. [ABSTRACT FROM AUTHOR]