1. [Interdisciplinary AWMF guideline for the treatment of primary antibody deficiencies].
- Author
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Krudewig J, Baumann U, Bernuth von H, Borte M, Burkhard-Meier U, Dueckers G, Foerster-Waldl E, Franke K, Habermehl P, Hönig M, Kern W, Kösters K, Kugel K, Lehrnbecher T, Liese J, Marks R, Müller GA, Müller R, Nadal D, Peter HH, Pfeiffer-Kascha D, Schneider M, Sitter H, Späth P, Wahn V, Welte T, and Niehues T
- Subjects
- Adult, Anti-Infective Agents therapeutic use, Child, Preschool, Combined Modality Therapy, Evidence-Based Medicine, Humans, Immunization, Passive, Physical Therapy Modalities, Quality Improvement, Randomized Controlled Trials as Topic, Vaccination, Cooperative Behavior, Immunologic Deficiency Syndromes therapy, Interdisciplinary Communication
- Abstract
Background: Currently, management of antibody deficient patients differs significantly among caregivers. Evidence and consensus based (S3) guidelines for the treatment of primary antibody deficiencies were developed to improve the management of these patients., Methods: Based on a thorough analysis of current evidence (systematic literature search in PubMed; deadline November 2011) 14 recommendations were finalized during a consensus meeting in Frankfurt in November 2011 using structured consensus methods (nominal group technique). Experts were nominated by their scientific societies/patient initiatives (Tab. 1)., Results: The guidelines focus on indication, practical issues and monitoring of immunoglobulin replacement therapy as well as on different routes of administration. Furthermore recommendations regarding supportive measures such as antiinfective therapy, vaccinations and physiotherapy are given. Combining literature evidence and experience of caregivers within this evidence and consensus based guidelines offers the chance to improve the quality of care for anti-body deficient patients., (© Georg Thieme Verlag KG Stuttgart · New York.)
- Published
- 2012
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