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Background: The novel amido and O-ferrocenyldithiophosphonates [FcP(S)(SH)(NHR¹)] (Fc = Fe(η5-C5H5)(η5-C5H4), R¹ = 1-(4-fluorophenylethyl and benzyloxycyclopentyl) and [FcP(S)(OR²)S-][H3N+C(CH3)3] (R² = myrtanyl) were synthesized by the reaction of [(FcPS2)]2 (Fc = Fe(η5-C5H5)(η5-C5H4)) and chiral amines, such as (S)-(–)-1-(4-fluorophenylethyl) amine and (1S,2S)-(+)-benzyloxycyclopentyl amine, and of (1S), (2S), (5S)-myrtanol in toluene. The reaction of ferrocenyldithiophosphonates and [Cu(PPh3)2]NO3 or AgNO3 and PPh3 gave rise to copper(I) and silver(I) complexes in THF. [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 were embedded into nanofibers and their antimicrobial activities on fibers were also investigated. Results: The compounds have been characterized by elemental analyses, IR, NMR (¹H-, 31P-) spectroscopy as well as MS measurements. Nanofibers were obtained by electrospinning method which is the simplest and most effective method to produce nanoscale fibers under strong electrical field. Antimicrobial activity of the compound 5, [Ag2{FcP (OMe)S2}2(PPh3)2], and [Cu(PPh3)2]NO3 on fibers were studied. Conclusions: In this study, the new dithiophosphonate ligands were synthesized and utilized in the preparation of copper(I) and silver(I) complexes with ferrocenyldithiophosphonate and triphenylphosphine. Then, the compounds [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 were added into the PAN solutions (Co-PAN dissolved in dimethylacetamide) and the solutions were electrospun onto microscope slides and PP meltblown surfaces. Antimicrobial activity of the compounds [Ag2{FcP(OMe)S2}2(PPh3)2] and [Cu(PPh3)2]NO3 on fibers were determined in vitro against two indicator strains; M. luteus NCIB and E. coli ATCC25922. The obtained results indicated that these metals showed moderate level antimicrobial activities. [ABSTRACT FROM AUTHOR]

The transport of Cu(II) ions from an aqueous solution into an aqueous receiving solution through a bulk liquid membrane containing a dithiophosphonate derivative (1) as a carrier was examined. The kinetic parameters were analyzed assuming 2 consecutive, irreversible first-order reactions. The influence of temperature and stirring rate on the kinetic parameters (k1, k2 Rmmax, tmax, Jdmax and Jamax) was also investigated. The membrane entrance rate, k1, and the membrane exit rate, k2 increased with increasing temperature and stirring rate. For the maximum membrane exit flux, Jamax, the activation energy was determined from the slope of the linear Arrhenius relationship to be 8.70 kcal mol-1, which indicates that the process is controlled by species diffusion. [ABSTRACT FROM AUTHOR]