1. Cor triatriatum sinister with dextrocardia in association with ostium secundum atrial septal defect, subpulmonary ventricular septal defect and bicuspid pulmonary valve in a pig.
- Author
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Shiga T, Kamiya Y, Ohkubo M, Miyamoto T, Kakinuma Y, Kayanuma H, Aoki T, Fujii Y, Aihara N, and Kamiie J
- Subjects
- Animals, Swine, Cor Triatriatum complications, Cor Triatriatum diagnosis, Cor Triatriatum veterinary, Pulmonary Valve, Heart Defects, Congenital veterinary, Heart Septal Defects, Atrial complications, Heart Septal Defects, Atrial diagnosis, Heart Septal Defects, Atrial veterinary, Heart Septal Defects, Ventricular complications, Heart Septal Defects, Ventricular diagnosis, Heart Septal Defects, Ventricular veterinary, Dextrocardia complications, Dextrocardia veterinary, Swine Diseases
- Abstract
Necropsy of a 52-day-old Camborough pig revealed numerous cardiac malformations. The positional relationship of the atria, ventricles and great vessels was a mirror image type (I, L and L): inverted arrangement of the atria, with a left-sided right atrium and right-sided left atrium (situs inversus); inverted arrangement of the ventricles, with a left-sided morphological right ventricle and right-sided morphological left ventricle (L-loop); and aortic valve to the front left relative to the pulmonary valve (L-malposed). The major malformations included an ostium secundum atrial septal defect, cor triatriatum sinister (CTS), a subpulmonary ventricular septal defect and a bicuspid pulmonary valve. Histological examination revealed myocyte hypertrophy, focal myocardial necrosis and calcification in the left morphological right ventricle of the heart. To the best of our knowledge, this is the first report of CTS in pigs. Although the individual malformations found in the present case are not unique, an unusual combination of these cardiac malformations has not been described in animals., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
- Published
- 2023
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