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Your search keyword '"Thatiane Lima Sampaio"' showing total 3 results
Start Over Author "Thatiane Lima Sampaio" Topic cornea
3 results on '"Thatiane Lima Sampaio"'

1. Causes of death and discard of donated corneal tissues: Federal District eye bank analysis 2014 -2017

Author

Diogo Souza Loiola, Sônia Nair Báo, Thayssa Neiva da Fonseca Victer, Micheline Borges Lucas, Maria Regina Catai Chalita, and Thatiane Lima Sampaio

Subjects
Córnea, Epidemiologia, Banco de olhos, Transplante de córnea, Brasil, Ophthalmology, RE1-994
Abstract

Abstract Objective: The aim of this study is to identify the causes for discarding corneas at the Eye Bank of the Federal District in Brasilia, Brazil, and describe the social and demographic variables and Causa Mortis of cornea donors from 2014 to 2017. Methods: We conducted an exploratory and social-epidemiologic descriptive study regarding cornea donation. The data base information was obtained from the corneal donor's medical records analysis. All of the potential donors' records (cause of death, cause of cornea discard, month of donation, age, gender, and time of death, corneal enucleation and preservation), from 2014 to 2017 were included in the study. Results: We looked at 1,574 corneal donor notifications. Demographic characteristics displayed significant differences in gender distribution (male, 74.8% and female, 25.2%), and the average donor age was 40 ± 15.9 years. 25% of the causes of death were from cardiovascular disease followed by 19.6% from sharp or blunt instrument injury, 14.2% resulted from multiple traumas. We described 3,074 donated corneas from the DF Eye Bank, where 2.6% has not been uptaken. Of those 3,074 corneal tissues, nearly 60% (n=1,836) have been transplanted and 40% (n=1,238) were discarded. Regarding the causes of discard, 68% (n=841) were due to positive or indeterminate serological blood tests and 39% (n=486) because of matureness (expired medium guaranteed period of corneal preservation). Conclusions: Specific issues such as violent causes of death, gender disproportion and total time of corneal processing can be better managed to reduce procurement times, and availability, of corneal tissue for transplantation.

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2. Factors influencing endothelial cell density of corneas for transplantation

Author

Sônia Nair Báo, Isabela Pereira Rodrigues, Maria Regina Chalita, Micheline Borges Lucas Cresta, Thayssa Neiva da Fonseca Victer, Thatiane Lima Sampaio, Anna Cláudia de Oliveira Queiroz, Daniela Ferreira Salomão Pontes, and Wildo Navegantes de Araújo

Subjects
030222 orthopedics, Transplantation, medicine.medical_specialty, genetic structures, business.industry, Coefficient of variation, Enucleation, Biomedical Engineering, Urology, Eye bank, High cell, Cell Biology, Biomaterials, Endothelial cell density, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Cornea, 030221 ophthalmology & optometry, medicine, business, Cause of death
Abstract

To evaluate factors affecting corneal endothelial cell density (ECD) under enucleation and preservation time studies at Eye Bank of the Federal District of Brazil. We conducted a case–control study collecting data from 1128 corneas where death-to-enucleation time and enucleation-to-preservation time were within 24 h. Low cell count were those corneas with an ECD less than 2000 cells/mm2 and high cell count was defined as those with ECD greater than 2000 cells/mm2. We calculated the independent risk factors related to: cause of death, donor age, death-to-enucleation time, enucleation-to-preservation time and primary graft failure. Correlation analysis was used to assess which parameters influence ECD: death-to-enucleation time, enucleation-to-preservation time, average cell area (AVE), coefficient of variation and percentage of hexagonal cells. Of the total number of corneas, 1004 had ECD data and were selected for the study. 87.4% (n = 877) had high cell counts with 2699 ± 412 cells/mm2. The mean donor age was 38.8 ± 16 years. The most common causes of death were external causes (48.6%, n = 488). Longer times from death-to-enucleation, up to 24 h were not associated with a decrease in ECD (OR 0.58; P = 0.44) or risk of graft survival (P = 0.74). Enucleation-to-preservation intervals greater than 12 h showed increased risk of graft survival (P = 0.04). AVE was the main parameter for ECD (R2 = 0.96, P

Published
2020
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3. Factors influencing endothelial cell density of corneas for transplantation

Author

Thatiane Lima, Sampaio, Isabela Pereira, Rodrigues, Micheline Borges Lucas, Cresta, Anna Cláudia de Oliveira, Queiroz, Thayssa Neiva da Fonseca, Victer, Daniela Ferreira Salomão, Pontes, Wildo Navegantes, de Araújo, Sônia Nair, Báo, and Maria Regina Catai, Chalita

Subjects
Adult, Cornea, Corneal Transplantation, Young Adult, Case-Control Studies, Endothelium, Corneal, Endothelial Cells, Humans, Cell Count, Organ Preservation, Middle Aged, Eye Banks, Tissue Donors
Abstract

To evaluate factors affecting corneal endothelial cell density (ECD) under enucleation and preservation time studies at Eye Bank of the Federal District of Brazil. We conducted a case-control study collecting data from 1128 corneas where death-to-enucleation time and enucleation-to-preservation time were within 24 h. Low cell count were those corneas with an ECD less than 2000 cells/mm

Published
2019

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