1. [Experimental and morphological study of the effect of antiangiogenic therapy on corneal neovessels].
- Author
-
Mamikonian VR, Voevodina TM, Fedorov AA, Budzinskaia MV, and Balaian ML
- Subjects
- Animals, Bevacizumab, Corneal Neovascularization diagnostic imaging, Corneal Neovascularization pathology, Corneal Stroma diagnostic imaging, Corneal Stroma pathology, Disease Models, Animal, Microscopy, Acoustic, Rabbits, Treatment Outcome, Vascular Endothelial Growth Factor A antagonists & inhibitors, Angiogenesis Inhibitors therapeutic use, Antibodies, Monoclonal, Humanized therapeutic use, Corneal Neovascularization drug therapy, Corneal Stroma drug effects, Photochemotherapy methods
- Abstract
The article presents the results of an experimental and morphological study of combined antiangiogenic effect of photodynamic therapy with Photosens photosensitizer and Avastin (bevacizumab) on neovascularization process in corneal stroma. The combined approach has demonstrated an advantage over separate application of these methods, what, however, has to be proved clinically.
- Published
- 2013