Search

Objectives: To determine the association of coronary artery ectasia in terms of its severity and vessels involved in diabetes patients and non-diabetes patients. Study Design: Cross-sectional study. Place and Duration of Study: Department of Cardiology, PAEC General Hospital, Islamabad Pakistan from Jun 2018 to Jun 2020. Methodology: All patients who underwent coronary angiography were included in this study. Two hundred patients (100 patients having diabetes and 100 patients not having diabetes) who presented with chest pain and chest heaviness were diagnosed with coronary artery ectasia on coronary angiography included in this study. Results: Two hundred patients, 100 patients had diabetes, and 100 patients had no diabetes. 71 (35.5%) of the patients were males, and 29 (14.5%) were females. The left anterior descending artery alone was responsible for 23% of Coronary Artery Ectasia, followed by the right coronary artery (16%) in diabetic patients. In patients with diabetes with multiple vessels, the left anterior descending artery and left circumflex artery were most frequently (21%) involved vessels, while left anterior descending and right coronary artery were observed to have Coronary artery ectasia in 16% of diabetes patients. Conclusion: No significant difference in the severity of coronary artery ectasia was noted among diabetes and non-diabetes patients. Left anterior descending was most frequently involved vessels in diabetes patients and right coronary artery in nondiabetes patients. Left anterior descending and left circumflex artery both had coronary artery ectasia in most of the diabetes patients and non-diabetes patients. [ABSTRACT FROM AUTHOR]

Objective: To describe the demographics; clinical, laboratory, echocardiographic findings; treatment and outcome in a cohort of children with Kawasaki disease in a tertiary care hospital. Methods: This is a descriptive, observational, retrospective cohort study conducted at Shifa International Hospital, Islamabad, from January 2013-June 2019. Children who met the criteria for Kawasaki disease according to the American Heart Association and American Academy of Pediatrics guidelines were included. Results: A total of 25 children who met the criteria of Kawasaki disease were included. Their mean age was 43 months (4-150 months). Majority (76%) were males. Eighteen (72%) had complete Kawasaki disease and 7 (28%) had incomplete Kawasaki disease. Fever (> five days) was present in 20 (80%) patients. Eight patients (32%) had echocardiographic changes, out of which two patients (25%) had complete Kawasaki disease and six patients (75%) had incomplete Kawasaki disease. Intravenous immunoglobulin was given to all patients. Fifteen children (60%) received intravenous immunoglobulin within 10 days of fever. None required a second dose. All patients received high dose aspirin at diagnosis which was reduced to antiplatelet dose after resolution of fever for ≥48hrs. Eighteen patients (72%) came for regular follow up. Follow up at 6 months showed complete resolution of echocardiographic changes in six patients (75%), 1 (12.5%) was lost to follow up and one (12.5%) child had persistent coronary artery dilatation. Conclusion: Complete KD was present in 72% of our cohort of children. Coronary artery abnormalities were present in one third of these children, at younger age and more common in those with incomplete KD but recovered in most. [ABSTRACT FROM AUTHOR]

Objective: To review the outcome of percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) of coronary arteries. Study Design: Cross sectional descriptive study. Place and Duration of Study: This study was carried out in the cardiology department of Pakistan Institute of Medical Sciences (PIMS) Islamabad, from Jan to Jul 2014. Material and Methods: In this study a total of 50 patients with chronic totally occluded coronary arteries having percutaneous coronary intervention (PCI) were included. The main outcome variable was frequency of procedural success. PCI and stent implantation were performed in a standard manner by expert interventionists having more than fifteen years' experience of doing PCI. Thrombolysis in Myocardial Infarction (TIMI) flow was noted at the end of CTO PCI by observer. Results: The mean age of the patients was 60.44 ± 9.214 years. There were 32 (64%) male patients with male to female ratio of 1.78:1. The CTO of left anterior descending (LAD) was seen in 23 (46%) patients, CTO of left circumflex (LCX) was seen in 14 (28%) patients and CTO of right coronary artery (RCA) was seen in 13 (26%) patients. In the study sample majority 40 (80%) of the patients had coronary artery disease (CAD) from 3-6 months and only 10 (20%) patients had a duration of CAD more than 6 months. The procedural success (TIMI flow ≥2) was achieved in 41 (82%) patients. Here was no significant association (p-value>0.05) of age and gender with procedural success. There was a highly significant (p-value<0.01) association between duration of CAD and procedural success. Conclusion: PCI is recommended in patients with CTO of coronary arteries as the success rate was very encouraging i.e. 82%, whenever the facility is available. [ABSTRACT FROM AUTHOR]

Objectives: To determine the association of coronary artery ectasia in terms of its severity and vessels involved in diabetes patients and non-diabetes patients. Study Design: Cross-sectional study. Place and Duration of Study: Department of Cardiology, PAEC General Hospital, Islamabad Pakistan from Jun 2018 to Jun 2020. Methodology: All patients who underwent coronary angiography were included in this study. Two hundred patients (100 patients having diabetes and 100 patients not having diabetes) who presented with chest pain and chest heaviness were diagnosed with coronary artery ectasia on coronary angiography included in this study. Results: Two hundred patients, 100 patients had diabetes, and 100 patients had no diabetes. 71 (35.5%) of the patients were males, and 29 (14.5%) were females. The left anterior descending artery alone was responsible for 23% of Coronary Artery Ectasia, followed by the right coronary artery (16%) in diabetic patients. In patients with diabetes with multiple vessels, the left anterior descending artery and left circumflex artery were most frequently (21%) involved vessels, while left anterior descending and right coronary artery were observed to have Coronary artery ectasia in 16% of diabetes patients. Conclusion: No significant difference in the severity of coronary artery ectasia was noted among diabetes and non-diabetes patients. Left anterior descending was most frequently involved vessels in diabetes patients and right coronary art ery in nondiabetes patients. Left anterior descending and left circumflex artery both had coronary artery ectasia in most of the diabet es patients and non-diabetes patients. [ABSTRACT FROM AUTHOR]