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2 results on '"Boddington NL"'

1. Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.

Author

Bermingham A, Chand MA, Brown CS, Aarons E, Tong C, Langrish C, Hoschler K, Brown K, Galiano M, Myers R, Pebody RG, Green HK, Boddington NL, Gopal R, Price N, Newsholme W, Drosten C, Fouchier RA, and Zambon M

Subjects
Animals, Coronavirus classification, Coronavirus pathogenicity, Coronavirus Infections microbiology, Coronavirus Infections virology, Disease Notification, Disease Reservoirs, Gene Expression Profiling, Humans, Intensive Care Units, London, Male, Middle Aged, Real-Time Polymerase Chain Reaction, Respiratory Insufficiency complications, Respiratory Insufficiency therapy, Saudi Arabia, Sensitivity and Specificity, Severe Acute Respiratory Syndrome microbiology, Severe Acute Respiratory Syndrome therapy, Coronavirus isolation & purification, Coronavirus Infections diagnosis, Patient Transfer, Severe Acute Respiratory Syndrome etiology, Travel
Abstract

Coronaviruses have the potential to cause severe transmissible human disease, as demonstrated by the severe acute respiratory syndrome (SARS) outbreak of 2003. We describe here the clinical and virological features of a novel coronavirus infection causing severe respiratory illness in a patient transferred to London, United Kingdom, from the Gulf region of the Middle East.

Published
2012

2. The United Kingdom public health response to an imported laboratory confirmed case of a novel coronavirus in September 2012.

Author

Pebody RG, Chand MA, Thomas HL, Green HK, Boddington NL, Carvalho C, Brown CS, Anderson SR, Rooney C, Crawley-Boevey E, Irwin DJ, Aarons E, Tong C, Newsholme W, Price N, Langrish C, Tucker D, Zhao H, Phin N, Crofts J, Bermingham A, Gilgunn-Jones E, Brown KE, Evans B, Catchpole M, and Watson JM

Subjects
Adult, Coronavirus Infections virology, Humans, London, Male, Saudi Arabia, Severe Acute Respiratory Syndrome virology, United Kingdom, Clinical Laboratory Techniques, Coronavirus isolation & purification, Coronavirus Infections diagnosis, Public Health Practice, Severe Acute Respiratory Syndrome diagnosis, Travel
Abstract

On 22 September 2012, a novel coronavirus, very closely related to that from a fatal case in Saudi Arabia three months previously, was detected in a previously well adult transferred to intensive care in London from Qatar with severe respiratory illness. Strict respiratory isolation was instituted. Ten days after last exposure, none of 64 close contacts had developed severe disease, with 13 of 64 reporting mild respiratory symptoms. The novel coronavirus was not detected in 10 of 10 symptomatic contacts tested.

Published
2012

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