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Your search keyword '"Early convalescence"' showing total 2 results
Start Over Descriptor "Early convalescence" Topic coronavirus infections
2 results on '"Early convalescence"'

1. Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase.

Author

Huang Y, Tan C, Wu J, Chen M, Wang Z, Luo L, Zhou X, Liu X, Huang X, Yuan S, Chen C, Gao F, Huang J, Shan H, and Liu J

Subjects
Adult, Aged, COVID-19, Chi-Square Distribution, China epidemiology, Cohort Studies, Convalescence, Exercise Test, Female, Follow-Up Studies, Forced Expiratory Volume, Humans, Incidence, Male, Middle Aged, Muscle Strength, Pandemics, Patient Discharge, Radiography, Thoracic methods, Respiratory Function Tests, Retrospective Studies, Risk Assessment, Severe Acute Respiratory Syndrome epidemiology, Spirometry methods, Tertiary Care Centers, Tomography, X-Ray Computed methods, Vital Capacity physiology, Coronavirus Infections diagnosis, Coronavirus Infections epidemiology, Pneumonia, Viral diagnosis, Pneumonia, Viral epidemiology, Respiratory Muscles physiopathology, Severe Acute Respiratory Syndrome diagnosis
Abstract

Objective: This study investigated the influence of Coronavirus Disease 2019 (COVID-19) on lung function in early convalescence phase., Methods: A retrospective study of COVID-19 patients at the Fifth Affiliated Hospital of Sun Yat-sen University were conducted, with serial assessments including lung volumes (TLC), spirometry (FVC, FEV1), lung diffusing capacity for carbon monoxide (DLCO),respiratory muscle strength, 6-min walking distance (6MWD) and high resolution CT being collected at 30 days after discharged., Results: Fifty-seven patients completed the serial assessments. There were 40 non-severe cases and 17 severe cases. Thirty-one patients (54.3%) had abnormal CT findings. Abnormalities were detected in the pulmonary function tests in 43 (75.4%) of the patients. Six (10.5%), 5(8.7%), 25(43.8%) 7(12.3%), and 30 (52.6%) patients had FVC, FEV1, FEV1/FVC ratio, TLC, and DLCO values less than 80% of predicted values, respectively. 28 (49.1%) and 13 (22.8%) patients had PImax and PEmax values less than 80% of the corresponding predicted values. Compared with non-severe cases, severe patients showed higher incidence of DLCO impairment (75.6%vs42.5%, p = 0.019), higher lung total severity score (TSS) and R20, and significantly lower percentage of predicted TLC and 6MWD. No significant correlation between TSS and pulmonary function parameters was found during follow-up visit., Conclusion: Impaired diffusing-capacity, lower respiratory muscle strength, and lung imaging abnormalities were detected in more than half of the COVID-19 patients in early convalescence phase. Compared with non-severe cases, severe patients had a higher incidence of DLCO impairment and encountered more TLC decrease and 6MWD decline.

Published
2020
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2. Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase

Author

Chaolin Chen, Fen Gao, Shican Yuan, Liyun Luo, Jian Wu, Zhenguo Wang, Xiaorong Zhou, Jing Liu, Yiying Huang, Cuiyan Tan, Meizhu Chen, Jin Huang, Xinran Liu, Xiaoling Huang, and Hong Shan

Subjects
Male, Vital Capacity, Severe Acute Respiratory Syndrome, Gastroenterology, 030218 nuclear medicine & medical imaging, Pulmonary function testing, Cohort Studies, Tertiary Care Centers, 0302 clinical medicine, Respiratory muscle strength, DLCO, Forced Expiratory Volume, Diffusing capacity, Early convalescence, Lung volumes, 030212 general & internal medicine, COVID-19, Lung function, media_common, medicine.diagnostic_test, Incidence, Convalescence, Middle Aged, respiratory system, Patient Discharge, Respiratory Muscles, Respiratory Function Tests, Female, Radiography, Thoracic, Coronavirus Infections, Adult, Spirometry, China, medicine.medical_specialty, media_common.quotation_subject, Pneumonia, Viral, Risk Assessment, 03 medical and health sciences, FEV1/FVC ratio, Internal medicine, medicine, Respiratory muscle, Humans, Muscle Strength, Pandemics, Aged, Retrospective Studies, lcsh:RC705-779, Chi-Square Distribution, business.industry, Research, lcsh:Diseases of the respiratory system, respiratory tract diseases, Exercise Test, Tomography, X-Ray Computed, business, Follow-Up Studies
Abstract

ObjectiveThis study investigated the influence of Coronavirus Disease 2019 (COVID-19) on lung function in early convalescence phase.MethodsA retrospective study of COVID-19 patients at the Fifth Affiliated Hospital of Sun Yat-sen University were conducted, with serial assessments including lung volumes (TLC), spirometry (FVC, FEV1), lung diffusing capacity for carbon monoxide (DLCO),respiratory muscle strength, 6-min walking distance (6MWD) and high resolution CT being collected at 30 days after discharged.ResultsFifty-seven patients completed the serial assessments. There were 40 non-severe cases and 17 severe cases. Thirty-one patients (54.3%) had abnormal CT findings. Abnormalities were detected in the pulmonary function tests in 43 (75.4%) of the patients. Six (10.5%), 5(8.7%), 25(43.8%) 7(12.3%), and 30 (52.6%) patients had FVC, FEV1, FEV1/FVC ratio, TLC, and DLCO values less than 80% of predicted values, respectively. 28 (49.1%) and 13 (22.8%) patients had PImax and PEmax values less than 80% of the corresponding predicted values. Compared with non-severe cases, severe patients showed higher incidence of DLCO impairment (75.6%vs42.5%,p = 0.019), higher lung total severity score (TSS) and R20, and significantly lower percentage of predicted TLC and 6MWD. No significant correlation between TSS and pulmonary function parameters was found during follow-up visit.ConclusionImpaired diffusing-capacity, lower respiratory muscle strength, and lung imaging abnormalities were detected in more than half of the COVID-19 patients in early convalescence phase. Compared with non-severe cases, severe patients had a higher incidence of DLCO impairment and encountered more TLC decrease and 6MWD decline.

Published
2020
Full Text
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