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Abstract: Microstructure, mechanical and corrosion properties of binary magnesium–dysprosium (Mg-5, 10, 15, 20wt.% Dy) alloys were investigated for medical applications. In the as-cast condition, the distribution of Dy is quite inhomogeneous. Mg–10Dy alloy exhibits a moderate tensile and compression yield strength, and the best elongation and corrosion resistance. After T4 (solutionizing) treatment, the distribution of Dy becomes homogeneous. The tensile and compression yield strength of all Mg–Dy alloys decreases. The elongation remains unchanged, while the corrosion resistance is largely improved after T4 treatment. [Copyright &y& Elsevier]

Abstract: Mn and Zn were selected to develop a Mg–Zn–Mn magnesium alloy for biomedical application due to the good biocompatibility of Zn and Mn elements. Microstructure, mechanical properties, corrosion properties and biocompatibility of the Mg–Zn–Mn alloys have been investigated by use of optical microscope, scanning electron microscope, tensile testing, and blood hemolysis and cell toxicity. Microstructure observation has shown that the addition of Zn and the extrusion significantly refined the grain size of both the as-cast and the extruded magnesium alloys, which mainly contributes to the high tensile strength and good elongation. Polarization test has shown Zn could accelerate the formation of a passivation film, which provides good protection to the magnesium alloy against simulate body fluid. Cell culture and hemolysis tests have shown that the magnesium alloy did not have cell toxicity, showing good cytocompatibility, but the alloy caused hemolysis to blood system. It was suggested that surface modification have to be adopted to improve the blood compatibility of the magnesium alloy for the application in blood environment. [Copyright &y& Elsevier]