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Start Over Author "Larsen, C. H." Topic coupling agents (chemistry)
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1. Copper/Titanium Catalysis Forms Fully Substituted Carbon Centers from the Direct Coupling of Acyclic Ketones, Amines, and Alkynes.

Author

Pierce, C. J., Larsen, C. H., and Nguyen, M.

Subjects
*CHEMICAL reactions, *CATALYSTS, *ALKENES, *KETONES, *COUPLING agents (Chemistry)
Abstract

The article discusses three-component couplings (3CC) of Acyclic Ketones, Amines and Alkynes using copper/titanium as catalysts. It mentions that Ketones could not be used in 3CC because it does not lead to the formation of in situ ketimine. It further mentions the findings of the research group of Catharine Larsen, Professor at University of California, California regarding the use of copper/titanium as catalysts to synthesize propargylamines directly from inactivated ketons.

Published
2013
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