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1. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placental Infection Is Associated With Massive Perivillous Fibrin Deposition at the Maternal-Fetal Interface: A Preliminary Study.

Author

Kotiloglu-Karaa, Esin, Kele, Beatrix, Kulasegaran-Shylini, Raghavendran, Broad, Claire E, Owoyemi, Dola, Martin, Joanne, MacPhail, Graham, Iliodromiti, Stamatina, Riddell, Anna, Alexander, Eliza, and Cutino-Moguel, Teresa

Subjects
*REVERSE transcriptase polymerase chain reaction, *COVID-19, *PLACENTA diseases, *IMMUNOHISTOCHEMISTRY, *SEVERITY of illness index, *FIBRIN, *DISEASE risk factors, *PREGNANCY
Abstract

We observed an increased frequency of massive perivillous fibrin deposition (MPFD) during the second coronavirus disease 2019 (COVID-19) pandemic wave dominated by the Alpha variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MPFD associated with 100% reverse transcription polymerase chain reaction (RT-PCR) positivity for SARS-CoV-2 and detection by immunohistochemistry. The Alpha variant was identified in all placentas with MPFD that could be sequenced. [ABSTRACT FROM AUTHOR]

Published
2022
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