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The global pandemic of SARS-CoV-2, or severe acute respiratory syndrome coronavirus, in 2020 claimed millions of lives globally. The clinical manifestation of this virus is called COVID-19, and it can cause everything from flu-like symptoms to severe clinical consequences and even death. The global health organization (WHO) created awareness campaigns to reduce infection rates and slow the virus's rapid spread because there was no proven medication that could treat this infection or lessen its problems with little to no negative effects on the health of the patients. Despite the fact that vaccinations have been created as preventative measures, people still prefer to use conventional herbal drugs because it offers exceptional health benefits and, with comparatively minor side effects, can either prevent a viral infection or restrict the development of serious symptoms through various mechanistic pathways. This thorough analysis offers empirical data clarifying the protective effect of various plants against SARS-CoV-2, opening the door for additional research to reevaluate plant-based extracts—rich in bioactive compounds—in more sophisticated clinical evaluations to determine their effect on COVID-19 patients. [ABSTRACT FROM AUTHOR]