7 results on '"Rubulotta, Francesca"'
Search Results
2. Development and validation of a tool to appraise guidelines on SARS-CoV-2 infection control strategies in healthcare workers.
- Author
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Subramaniam A, Ponnapa Reddy M, Kadam U, Zubarev A, Lim Z, Anstey C, Bihari S, Haji J, Luo J, Mitra S, Ramanathan K, Rajamani A, Rubulotta F, Svensk E, and Shekar K
- Subjects
- Health Personnel, Humans, Infection Control, Infectious Disease Transmission, Patient-to-Professional, Pandemics prevention & control, SARS-CoV-2, COVID-19
- Abstract
Background: Clinical guidelines on infection control strategies in healthcare workers (HCWs) play an important role in protecting them during the severe acute respiratory syndrome coronavirus 2 pandemic. Poorly constructed guidelines that are incomprehensive and/or ambiguous may compromise HCWs' safety., Objective: The objective of this study was to develop and validate a tool to appraise guidelines on infection control strategies in HCWs based on the guidelines published early in the coronavirus disease 2019 pandemic., Design, Setting, and Outcomes: A three-stage, web-based, Delphi consensus-building process among a panel of diverse HCWs and healthcare managers was performed. The tool was validated by appraising 40 international, specialty-specific, and procedure-specific guidelines along with national guidelines from countries with a wide range of gross national income., Results: Overall consensus (≥75%) was reached at the end of three rounds for all six domains included in the tool. The Delphi panel recommended an ideal infection control guideline should encompass six domains: general characteristics (domain 1), engineering recommendations (domain 2), personal protective equipment (PPE) use (domain 3), and administrative aspects (domain 4-6) of infection control. The appraisal tool performed well across the six domains, and the inter-rater agreement was excellent for the 40 guidelines. All included guidelines performed relatively better in domains 1-3 than in domains 4-6, and this was more evident in guidelines originating from lower income countries., Conclusion: The guideline appraisal tool was robust and easy to use. Engineering recommendations aspects of infection control, administrative measures that promote optimal PPE use, and HCW wellbeing were generally lacking in assessed guidelines. This tool may enable health systems to adopt high-quality HCW infection control guidelines during the severe acute respiratory syndrome coronavirus 2 pandemic and may also provide a framework for future guideline development., (Copyright © 2021 Australian College of Critical Care Nurses Ltd. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2022
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- View/download PDF
3. Anxiety among front-line health-care workers supporting patients with COVID-19: A global survey.
- Author
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Cag Y, Erdem H, Gormez A, Ankarali H, Hargreaves S, Ferreira-Coimbra J, Rubulotta F, Belliato M, Berger-Estilita J, Pelosi P, Blot S, Lefrant JY, Mardani M, Darazam IA, Cag Y, and Rello J
- Subjects
- Adult, Age Factors, Female, Health Care Surveys, Health Surveys, Humans, Male, Middle Aged, Sex Factors, Anxiety epidemiology, COVID-19 diagnosis, COVID-19 therapy, Nurses statistics & numerical data, Occupational Stress epidemiology, Personal Protective Equipment statistics & numerical data, Physicians statistics & numerical data
- Abstract
Objective: We aimed to explore anxiety status across a broad range of HCWs supporting patients with COVID-19 in different global regions., Method: This was an international online survey in which participation was on voluntary basis and data were submitted via Google Drive, across a two-week period starting from March 18, 2020. The Beck Anxiety Inventory was used to quantify the level of anxiety., Results: 1416 HCWs (70.8% medical doctors, 26.2% nurses) responded to the survey from 75 countries. The distribution of anxiety levels was: normal/minimal (n = 503, 35.5%), low (n = 390, 27.5%); moderate (n = 287, 20.3%), and severe (n = 236, 16.7%). According to multiple generalized linear model, female gender (p = 0.001), occupation (ie, being a nurse dealing directly with patients with COVID-19 [p = 0.017]), being younger (p = 0.001), reporting inadequate knowledge on COVID-19 (p = 0.005), having insufficient personal protective equipment (p = 0.001) and poor access to hand sanitizers or liquid soaps (p = 0.008), coexisting chronic disorders (p = 0.001) and existing mental health problems (p = 0.001), and higher income of countries where HCWs lived (p = 0.048) were significantly associated with increased anxiety., Conclusions: Front-line HCWs, regardless of the levels of COVID-19 transmission in their country, are anxious when they do not feel protected. Our findings suggest that anxiety could be mitigated ensuring sufficient levels of protective personal equipment alongside greater education and information., (Copyright © 2020 Elsevier Inc. All rights reserved.)
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- 2021
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- View/download PDF
4. The COVID-19 vaccination acceptance/hesitancy rate and its determinants among healthcare workers of 91 countries: a multicenter cross-sectional study
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Askarian, Mehrdad, Semenov, Aleksandr, Llopis, Ferran, Rubulotta, Francesca, Dragovac, Gorana, Pshenichnaya, Natalia, Assadian, Ojan, Ruch, Yvon, Shayan, Zahra, Padilla Fortunatti, Cristobal, Lucey, Daniel, Almohaizeie, Abdullah, Kamal, Abu Hena Mostafa, Ogunshe, Adenike, Konkayev, Aidos, Beg, Asim, Primerano, Enzo, Amer, Fatma, Kumari Pilli, Hema Prakash, Hung, Ivan, Ayoade, Folusakin, Lefrant, Jean Yves, Zajkowska, Joanna, Rello, Jordi, Kazi, Momin, Taghrir, Mohammad Hossein, Blot, Stijn, Leib, Stephen, Hosseinpour, Parisa, Hosseinpour, Hamidreza, Erfani, Amirhossein, Borazjani, Roham, Akbarialiabad, Hossein, Najafi, Masoud, Askarian, Ardalan, Erdem, Hakan, Institut Català de la Salut, [Askarian M] Department of Community Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Health Behavior Science Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. [Semenov A] Ekaterinburg Research Institute of Viral Infections SRC VB Vector, Ekaterinburg, Russia. [Llopis F] Emergency Department, Bellvitge University Hospital, l’Hospitalet de Llobregat, Spain. [Rubulotta F] Department of Intensive Care Medicine, Charing Cross Hospital, Imperial College, NHS Trust, London, UK. [Dragovac G] Department of Epidemiology, Faculty of Medicine, University of Novi Sad, Serbia. Center of Disease Prevention and Control, Institute of Public Health of Vojvodina, Novi Sad, Serbia. [Pshenichnaya N] Clinical Department of Infectious Pathology, Central Research Institute of Epidemiology, Moscow, Russia. [Rello J] Grup de Recerca Clínica/Innovació en la Pneumònia i Sèpsia, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CHRU Nimes, Nimes, France, and Vall d'Hebron Barcelona Hospital Campus
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HDI ,vaccination coverage ,Human Development Index ,COVID-19 ,COVID-19 vaccines ,health ,610 Medicine & health ,Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES] ,health personnel ,Personal mèdic ,Medicine and Health Sciences ,virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES] ,570 Life sciences ,biology ,personnel ,COVID-19 (Malaltia) - Vacunació - Abstract
The aim of this study was to investigate the COVID-19 vaccination acceptance rate and its determinants among healthcare workers in a multicenter study. This was a cross-sectional multi-center survey conducted from February 5 to April 29, 2021. The questionnaire consisted of 26 items in 6 subscales. The English version of the questionnaire was translated into seven languages and distributed through Google Forms using snowball sampling; a colleague in each country was responsible for the forward and backward translation, and also the distribution of the questionnaire. A forward stepwise logistic regression was utilized to explore the variables and questionnaire factors tied to the intention to COVID-19 vaccination. 4630 participants from 91 countries completed the questionnaire. According to the United Nations Development Program 2020, 43.6 % of participants were from low Human Development Index (HDI) regions, 48.3 % high and very high, and 8.1 % from medium. The overall vaccination hesitancy rate was 37 %. Three out of six factors of the questionnaire were significantly related to intention to the vaccination. While ���Perceived benefits of the COVID-19 vaccination��� (OR: 3.82, p-value, EXCLI Journal; 21:Doc93; ISSN 1611-2156
- Published
- 2022
5. Development and Validation of Tool to Appraise Guidelines on SARS-CoV-2 Infection Prevention Strategies in Healthcare Workers
- Author
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Ashwin Subramaniam, Rajamani Arvind, Svensk Erik, Shekar Kiran, Ramanathan Kollengode, Luo Jinghang, Mara Neil, Kadam Umesh, Lim Zhengjie, Reddy Mallikarjuna, Bihari Shailesh, Mitra Saikat, Karunanithi Subhathra, Rubulotta Francesca, Haji Jumana, Zubarev Alexander, and Anstey Chris
- Subjects
business.industry ,media_common.quotation_subject ,education ,Declaration ,COVID-19 ,Guideline ,Coronavirus ,Gross national income ,Nursing ,Health care ,Pandemic ,Medicine ,Infection control ,Quality (business) ,business ,Personal protective equipment ,media_common - Abstract
Background: Clinical guidelines on infection prevention strategies in healthcare workers (HCWs) play an important role in protecting them during the SARS-CoV-2 pandemic. Poorly constructed guidelines that are not comprehensive and are ambiguous may compromise HCWs’ safety. We aimed to develop and validate a tool to appraise guidelines on infection prevention strategies in HCWs. Methods: A 3-round, web-based, delphi consensus-building process among a diverse group of HCWs and healthcare managers was utilised. We validated the tool by appraising 40 international, specialty-specific and procedure-specific guidelines along with national guidelines from countries with a wide range of gross national income. Findings: Overall consensus (≥75%) was reached at the end of three rounds for all six domains included in the tool. The chosen domains allowed appraisal of guidelines in relation to general characteristics (domain-1), recommendations on engineering (domain-2) and administrative aspects (domain 4-6) of infection prevention, as well as personal protection equipment (PPE) use (domain-3). The appraisal tool performed well across all domains and inter-rater agreement was excellent. All included guidelines performed relatively better in domains 1-3 compared with domains 4-6 and this was more evident in guidelines originating from lower income countries. Interpretation: The guideline appraisal tool was robust and easy to use. Recommendations on engineering aspects of infection prevention, administrative measures that promote optimal PPE use and HCW wellbeing were generally lacking in assessed guidelines. This tool may enable health systems to adopt high quality HCW infection prevention guidelines during SARS-CoV-2 pandemic and may also provide a framework for future guideline development. Funding Statement: No funding received. Declaration of Interests: Authors have nothing to disclose and they have no conflicts of interest. Ethics Approval Statement: The authors stated that this research did not include collection or distribution of any sensitive medical information and hence ethics approval was not required.
- Published
- 2020
6. Case Fatality Rates for Patients with COVID-19 Requiring Invasive Mechanical Ventilation. A Meta-analysis.
- Author
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Zheng Jie Lim, Subramaniam, Ashwin, Reddy, Mallikarjuna Ponnapa, Blecher, Gabriel, Kadam, Umesh, Afroz, Afsana, Billah, Baki, Ashwin, Sushma, Kubicki, Mark, Bilotta, Federico, Curtis, J. Randall, and Rubulotta, Francesca
- Subjects
ARTIFICIAL respiration ,COVID-19 ,MORTALITY ,HETEROGENEITY ,META-analysis - Abstract
Rationale: Initial reports of case fatality rates (CFRs) among adults with coronavirus disease (COVID-19) receiving invasive mechanical ventilation (IMV) are highly variable.Objectives: To examine the CFR of patients with COVID-19 receiving IMV.Methods: Two authors independently searched PubMed, Embase, medRxiv, bioRxiv, the COVID-19 living systematic review, and national registry databases. The primary outcome was the "reported CFR" for patients with confirmed COVID-19 requiring IMV. "Definitive hospital CFR" for patients with outcomes at hospital discharge was also investigated. Finally, CFR was analyzed by patient age, geographic region, and study quality on the basis of the Newcastle-Ottawa Scale.Measurements and Results: Sixty-nine studies were included, describing 57,420 adult patients with COVID-19 who received IMV. Overall reported CFR was estimated as 45% (95% confidence interval [CI], 39-52%). Fifty-four of 69 studies stated whether hospital outcomes were available but provided a definitive hospital outcome on only 13,120 (22.8%) of the total IMV patient population. Among studies in which age-stratified CFR was available, pooled CFR estimates ranged from 47.9% (95% CI, 46.4-49.4%) in younger patients (age ≤40 yr) to 84.4% (95% CI, 83.3-85.4%) in older patients (age >80 yr). CFR was also higher in early COVID-19 epicenters. Overall heterogeneity is high (I2 >90%), with nonsignificant Egger's regression test suggesting no publication bias.Conclusions: Almost half of patients with COVID-19 receiving IMV died based on the reported CFR, but variable CFR reporting methods resulted in a wide range of CFRs between studies. The reported CFR was higher in older patients and in early pandemic epicenters, which may be influenced by limited ICU resources. Reporting of definitive outcomes on all patients would facilitate comparisons between studies.Systematic review registered with PROSPERO (CRD42020186997). [ABSTRACT FROM AUTHOR]
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- 2021
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7. Antibiotic use in patients with COVID-19: a 'snapshot' Infectious Diseases International Research Initiative (ID-IRI) survey.
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Beović, Bojana, Doušak, May, Ferreira-Coimbra, João, Nadrah, Kristina, Rubulotta, Francesca, Belliato, Mirko, Berger-Estilita, Joana, Ayoade, Folusakin, Rello, Jordi, and Erdem, Hakan
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COVID-19 ,COMMUNICABLE diseases ,ANTIBIOTICS ,STAPHYLOCOCCUS aureus ,MUPIROCIN ,PHYSICIANS ,COMMUNITY-acquired pneumonia ,FLUOROQUINOLONES ,VIRAL pneumonia ,COVID-19 pandemic ,EPIDEMICS ,MEDICAL prescriptions - Abstract
Background: Antibiotics may be indicated in patients with COVID-19 due to suspected or confirmed bacterial superinfection.Objectives: To investigate antibiotic prescribing practices in patients with COVID-19.Methods: We performed an international web-based survey and investigated the pattern of antibiotic use as reported by physicians involved in treatment of COVID-19. SPSS Statistics version 25 was used for data analysis.Results: The survey was completed by 166 participants from 23 countries and 82 different hospitals. Local guidelines for antibiotic use in COVID-19 patients were reported by 61.8% (n = 102) of participants and for 82.9% (n = 136) they did not differ from local community-acquired pneumonia guidelines. Clinical presentation was recognized as the most important reason for the start of antibiotics (mean score = 4.07 and SD = 1.095 on grading scale from 1 to 5). When antibiotics were started, most respondents rated as the highest the need for coverage of atypical pathogens (mean score = 2.8 and SD = 0.99), followed by Staphylococcus aureus (mean score = 2.67 and SD = 1.05 on bi-modal scale, with values 1 and 2 for disagreement and values 3 and 4 for agreement). In the patients on the ward, 29.1% of respondents chose not to prescribe any antibiotic. Combination of β-lactams and macrolides or fluoroquinolones was reported by 52.4% (n = 87) of respondents. In patients in the ICU, piperacillin/tazobactam was the most commonly prescribed antibiotic. The mean reported duration of antibiotic treatment was 7.12 (SD = 2.44) days.Conclusions: The study revealed widespread broad-spectrum antibiotic use in patients with COVID-19. Implementation of antimicrobial stewardship principles is warranted to mitigate the negative consequences of antibiotic therapy. [ABSTRACT FROM AUTHOR]- Published
- 2020
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