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Background: The control measures of the coronavirus disease 2019 (COVID-19) pandemic had influenced the activity of the influenza virus, and we were wondering the knowledge, attitudes, and practices (KAP) toward seasonal influenza vaccine among college students were having at the context of the COVID-19 pandemic., Methods: Online questionnaire survey of the college students was conducted and the data was collected anonymously, cross-sectional study were used to describe the distribution of the KAP., Results: There were 815 respondents in our study. Most participants have a high recognition of the effectiveness and safety of the influenza vaccine. However, a low awareness rate of influenza vaccine knowledge and vaccination rate (18%) against influenza was observed among college students. The education level and major would have a higher weight on the influence of KAP among the college students. Binary logistic regression analysis showed that the sex (OR = 2.163, p < .001), age (OR = 2.242, p < .001), heard of the influenza vaccine (OR = 2.655, p = .014), and "How necessary do you think vaccinating every year is?" (OR = 3.947, p < .001) of the college students were the main factors that affect the KAP on influenza vaccination., Conclusions: Our study provided an insight into the KAP of influenza vaccine among college students in South China. The vaccination rate and acceptability of influenza vaccine in college students are higher than that in the whole population., (© 2023 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd.)

Background: To analyze the epidemic characteristics of the human rhinovirus (HRV) outbreaks in Guangzhou, China, in 2020., Methods: Descriptive epidemiological methods were used to analyze the HRV-related outbreaks in Guangzhou, 2020., Results: Seventeen outbreaks were reported in 2020 during the coronavirus disease 2019 (COVID-19) pandemic in Guangzhou, a total of 465 patients (290 males and 175 females) were enrolled, with a median age of 10. A total of 223 (47.96%) had been tested for HRV, 89 (39.91%) of which were positive; 344/465 (73.98%) had a fever, 138/465 (29.68%) had a runny nose, 139/465 (29.89%) had a sore throat, 86/465 (18.49%) had a cough, 41/465 (8.82%) had a headache, and 37/465 (7.96%) had a sneeze. Patients at age of 13-15 had the highest rate of sore throat and runny nose, patients aged 11-12 had the highest rate of sneezing, and patients at age of 12-14 had the highest rate of positive rate. Patients tested positive had a higher rate of fever (χ 2  = 11.271, p = .001), cough (χ 2  = 6.987, p = .008), runny nose (χ 2  = 7.980, p = .005), and sneeze (χ 2  = 4.676, p = .031)., Conclusion: The HRV was restored during the fighting of the COVID-19 pandemic. The conventional COVID-19 control measures were not effective enough in preventing rhinovirus. More appropriate control measures should be used to control HRV., (© 2022 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd.)

Coronavirus disease 2019 (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 1-3 and individuals with COVID-19 have symptoms that can be asymptomatic, mild, moderate or severe 4,5 . In the early phase of infection, T- and B-cell counts are substantially decreased 6,7 ; however, IgM 8-11 and IgG 12-14 are detectable within 14 d after symptom onset. In COVID-19-convalescent individuals, spike-specific neutralizing antibodies are variable 3,15,16 . No specific drug or vaccine is available for COVID-19 at the time of writing; however, patients benefit from treatment with serum from COVID-19-convalescent individuals 17,18 . Nevertheless, antibody responses and cross-reactivity with other coronaviruses in COVID-19-convalescent individuals are largely unknown. Here, we show that the majority of COVID-19-convalescent individuals maintained SARS-CoV-2 spike S1- and S2-specific antibodies with neutralizing activity against the SARS-CoV-2 pseudotyped virus, and that some of the antibodies cross-neutralized SARS-CoV, Middle East respiratory syndrome coronavirus or both pseudotyped viruses. Convalescent individuals who experienced severe COVID-19 showed higher neutralizing antibody titres, a faster increase in lymphocyte counts and a higher frequency of CXCR3 + T follicular help (T FH ) cells compared with COVID-19-convalescent individuals who experienced non-severe disease. Circulating T FH cells were spike specific and functional, and the frequencies of CXCR3 + T FH cells were positively associated with neutralizing antibody titres in COVID-19-convalescent individuals. No individuals had detectable autoantibodies. These findings provide insights into neutralizing antibody responses in COVID-19-convalescent individuals and facilitate the treatment and vaccine development for SARS-CoV-2 infection.

On 31 May 2021, the Political Bureau of the Central Committee of the Communist Party of China proposed the policy that a couple can have three children, and rolled out more supportive measures to further optimize the fertility policies. However, while the Chinese government is further optimizing its fertility policy, the sudden outbreak of COVID-19 is raging around the world, which threatens the implementation of China's fertility optimization policy. Based on this, this paper firstly explores the impact of COVID-19 on women's fertility intentions. Secondly, based on the Theory of Planned Behavior, this paper constructs a structural equation model to quantitatively reveal the specific factors that affect women's fertility intentions under the epidemic, as well as their impact paths, and then puts forward corresponding suggestions for the government to solve the problem of fertility, aiming at delaying population aging and optimizing population structure. The research results show that: (1) COVID-19 lowers the fertility intentions of women of childbearing age. (2) During the pandemic, economic pressure emerged as the biggest factor affecting women's fertility intentions. The decline in income caused by the pandemic has become an important factor in preventing women from having children. (3) The conflict between work and childbearing is still an important factor affecting the fertility intentions of women of childbearing age. The government's provision of perfect childcare services and their strengthening of the protection of women's employment rights and interests will greatly reduce women's anxiety about childbearing. [ABSTRACT FROM AUTHOR]

• The latest summary of the COVID-19 outbreak in China; • There might be an oral-fecal transmission of the virus; • Aggregates and consolidates the epidemiology, clinical manifestations, diagnosis, treatments and preventions of this new type of coronavirus. There is a current worldwide outbreak of the novel coronavirus Covid-19 (coronavirus disease 2019; the pathogen called SARS-CoV-2; previously 2019-nCoV), which originated from Wuhan in China and has now spread to 6 continents including 66 countries, as of 24:00 on March 2, 2020. Governments are under increased pressure to stop the outbreak from spiraling into a global health emergency. At this stage, preparedness, transparency, and sharing of information are crucial to risk assessments and beginning outbreak control activities. This information should include reports from outbreak site and from laboratories supporting the investigation. This paper aggregates and consolidates the epidemiology, clinical manifestations, diagnosis, treatments and preventions of this new type of coronavirus. [ABSTRACT FROM AUTHOR]

The impact of COVID-19 control measures on the morbidity of varicella, herpes zoster, rubella and measles in Guangzhou, China The Coronavirus Disease 2019 (COVID-19) pandemic have now becoming a worldwide catastrophe, as of September 9, 2020, the conformed COVID-19 cases are 27,486,960, and 894,983 deaths are reported.1 Varicella (chickenpox), rubella and measles are also infectious diseases caused by the respiratory virus. We have noticed that the reported varicella cases, rubella cases, and measles cases in Guangzhou City, China are dramatically decreased during the fight against COVID-19 pandemic. [Extracted from the article]